Top 10 Fluoride Varnishes for Dentistry.

How to Choose a Fluoride Varnish

These ten rows are in-office fluoride varnishes, and two of them are the same VOCO Profluorid 5% sodium fluoride varnish in different packs: single-dose units, and a 10 ml tube. Vanish is a white varnish with tri-calcium phosphate; the block names fluoride, calcium, and phosphate and does not print a percent or a ppm figure. NUPRO, Kolorz ClearShield, and MI Varnish print 5% sodium fluoride. FluoroDose, Duraflor, Vella, and Embrace also print 22,600 ppm. MI Varnish adds Recaldent (CPP-ACP). Embrace adds CXP, a xylitol-coated calcium and phosphate system.

Foams and gels are a different delivery: the in-office fluoride list. Tray applicators are on the fluoride trays list. A desensitizer that is not this varnish class sits on the desensitizer guide. Pit-and-fissure resin is the sealant guide. Dealer prices and star counts are omitted. The numbers below follow this catalog’s order.

Buying criteria that change the box

• Pack you can count — Profluorid single-dose boxes are printed as 50 or 100 units. The tube row is 10 ml. FluoroDose is a 0.3 ml LolliPack, in boxes of 30, 100, or more. The MI Varnish photo says 50/pkg; the spec block says various unit sizes. The other rows say single-use, bulk, or assorted boxes without a fixed count, so no count is added.
• What the listing adds to fluoride — Vanish: TCP plus calcium and phosphate. MI Varnish: CPP-ACP. Embrace: CXP, no mixing, and a fluorapatite line. Profluorid and Vella and Duraflor name xylitol as the sweetener. Kolorz names watermelon or bubblegum and a clear film.
• How it is described on the tooth — Profluorid: transparent white, sets in seconds on saliva, adheres to moist enamel and dentin. NUPRO: hydrogenated rosin and urethane resin, brush-on, moist surfaces, and a “half the wear time” line. FluoroDose: white that dries clear, 6–8 hours on the tooth, no prophy before use. Duraflor: sets on saliva, and the block also calls it a cavity liner. Vella: dries to a natural tooth color, dual-fiber brush. MI Varnish: opaque white that dries clear, creamy. Kolorz: clear, no clump or grit in the listing’s words.
• Lines that stay the listing’s lines — FluoroDose’s “FDA-approved for dentinal sensitivity,” Duraflor’s “up to 6 months” of sensitivity relief, NUPRO’s shorter wear time, and Embrace’s fluorapatite step are printed claims. They are not new measurements.

Product	What the row is	Fluoride the listing prints	Pack the listing prints	Watch-out
Profluorid single dose	5% NaF varnish, unit dose	5% sodium fluoride; ppm not printed	50 or 100 units	VOCO. Xylitol. Transparent white. Sets on saliva. Germany.
Vanish	White varnish with TCP	Fluoride, calcium, and phosphate; percent not printed	Single-use or bulk; count not fixed	3M. Moisture-tolerant. Do not treat it as 5% or 22,600 ppm.
NUPRO	5% NaF white varnish	5% sodium fluoride; ppm not printed	Traditional or easy-application units	Dentsply. Rosin and urethane base. “Half the wear time” is the listing’s line.
Profluorid tube	Same 5% NaF varnish, tube	5% sodium fluoride; ppm not printed	10 ml	VOCO. Same formula claims as the unit dose. The tube is the difference.
Kolorz ClearShield	5% NaF, clear film	5% sodium fluoride; ppm not printed	Unit or tube; count not printed	DMG. Watermelon or bubblegum.
FluoroDose	5% NaF unit dose	5% sodium fluoride, 22,600 ppm	0.3 ml LolliPack; boxes of 30, 100, or more	Centrix. Benda brush. 6–8 hours on the tooth. No prophy.
Duraflor	5% NaF varnish	5% sodium fluoride, 22,600 ppm	Single-dose or bulk; count not printed	Medicom. Xylitol. Cavity-liner line. Canada.
Vella	5% NaF with xylitol	5% sodium fluoride, 22,600 ppm	Assorted boxes; count not printed	Preventive Technologies. Dual-fiber brush. USA.
MI Varnish	5% NaF with CPP-ACP	5% sodium fluoride; ppm not printed	Photo says 50/pkg; spec says various	GC America. Recaldent. Opaque white, dries clear.
Embrace	5% NaF with CXP	5% sodium fluoride, 22,600 ppm	Single-dose or kits; count not printed	Pulpdent. No mixing. Fluorapatite line is the listing’s.

1. Profluorid Varnish — single dose, VOCO

VOCO Profluorid single dose is a 5% sodium fluoride varnish in unit-dose packaging, printed as 50 or 100 units depending on the box. The block says a thin, spreadable varnish, high immediate fluoride release, a set in seconds after saliva contact, and adhesion to moist enamel and dentin. Color: transparent white. Sweetener: xylitol. Free-from list printed: tree nuts, peanuts, corn, shellfish, eggs, milk protein, soy, gluten, and no artificial coloring, saccharin, aspartame, triclosan, or petroleum. Country: Germany. Flavors are “assorted.” A ppm figure is not printed.

Who it is for: Unit-dose 5% NaF when the hygiene visit wants a xylitol-sweetened varnish that the listing says will set on saliva and stick to a moist surface.

Tradeoff: This is the same formula story as the 10 ml tube below. The pack is the choice. “High immediate fluoride release” is the listing’s line, and no ppm is added to match the 22,600 ppm rows.

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2. Vanish White Varnish — 3M TCP

3M Vanish White Varnish is a professional topical varnish with tri-calcium phosphate. The block names fluoride, calcium, and phosphate, a white film, and adhesion to moist enamel and dentin. Uses named: topical fluoride protection, early carious lesions, and dentin hypersensitivity, for pediatric and adult patients. Packaging is “single-use doses or bulk packs.” Percent sodium fluoride and ppm are not printed. Country: USA.

Who it is for: A white TCP varnish when the mineral line you are buying is fluoride plus calcium and phosphate, and the box you want is 3M’s.

Tradeoff: The title does not say 5% sodium fluoride. This guide does not assign 22,600 ppm or a unit count. “Targeted and sustained release” is the listing’s description of TCP.

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3. NUPRO White Varnish — Dentsply

NUPRO 5% Sodium Fluoride White Varnish, from Dentsply Professional, is a brush-on varnish the listing says seals dentinal tubules. The base is hydrogenated rosin and urethane resin. The block says no clumping, dripping, or stinging, application on wet enamel, and a wear time “half that of traditional varnishes.” Packaging: traditional or easy-application units. A unit count and a ppm figure are not printed. Country: USA.

Who it is for: A 5% NaF white varnish when the base you want named is rosin and urethane, on a moist tooth, from Dentsply Sirona’s NUPRO line.

Tradeoff: “Half the wear time” is the listing’s comparison, not a minute count. Ppm is not on the page, so it is not copied from FluoroDose.

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4. Profluorid Varnish — 10 ml tube, VOCO

The Profluorid 10 ml tube is the same 5% sodium fluoride varnish as the single-dose row: thin consistency, set within seconds on saliva, moist enamel and dentin, transparent white, xylitol, and the same allergen and additive exclusions, including no red dye. Country: Germany. The form line is the 10 ml tube. A box count is not printed.

Who it is for: The tube when unit-dose wrappers are the thing you are trying to avoid, and the formula claims you already accepted on the single-dose row.

Tradeoff: Nothing in the formula block distinguishes this tube from the unit dose. Buy it as a pack change. A ppm figure is still not printed.

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5. Kolorz ClearShield — DMG

Kolorz ClearShield is a 5% sodium fluoride varnish from DMG America. The listing says it goes on clear, without clumping or a gritty feeling, in watermelon or bubblegum. Application is brush-on, as a single-use unit or a tube depending on the package. Uses named: preventive fluoride after a cleaning, including pediatric visits. Ppm, unit count, and a set time are not printed. Country: USA.

Who it is for: A clear 5% NaF varnish when the flavor pair is watermelon or bubblegum and a visible white film is the thing you are avoiding.

Tradeoff: “No discoloration” is the listing’s appearance line. It does not print 22,600 ppm, a wear time, or a sweetener other than the two flavors.

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6. FluoroDose — Centrix

Centrix FluoroDose is a 5% sodium fluoride varnish at 22,600 ppm in a 0.3 ml LolliPack. Each unit includes a Benda brush for mixing before the brush-on. The block says no prophylaxis before use, a white varnish that dries clear, a set in seconds on saliva, and 6–8 hours on the tooth. The sensitivity indication is printed as FDA-approved for dentinal sensitivity. Boxes: 30, 100, or more. Country: USA.

Who it is for: A pre-measured 0.3 ml dose with the brush in the pack, when 22,600 ppm and a 6–8 hour wear line are the numbers you want on the box.

Tradeoff: “Maximum allowed fluoride dosage” and the FDA line are the listing’s words. The wear time is hours on the tooth, which is a different claim from Duraflor’s “up to 6 months” of relief.

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7. Duraflor — Medicom

Duraflor is a 5% sodium fluoride varnish from AMD Medicom at 22,600 ppm, sweetened with xylitol. The block says it sets on saliva, is a single-step brush-on, and may be used as a cavity liner. “Clinically proven relief from sensitivity for up to 6 months” is printed as the duration. Packaging: single-dose or bulk, without a fixed count. Country: Canada.

Who it is for: A 22,600 ppm xylitol varnish when the extra line you are buying is the cavity-liner use, from Medicom.

Tradeoff: The six-month figure is the listing’s sensitivity claim, not a wear-time in hours and not a head-to-head against FluoroDose. Unit count is not printed.

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8. Vella Varnish — xylitol

Vella is a 5% sodium fluoride varnish with 22,600 ppm fluoride and xylitol, from Preventech / Preventive Technologies. The block says a less sticky consistency, a dry-down to a natural tooth color, and an applicator brush with twice as many fibers. Uses named: caries prevention and dentin hypersensitivity. Packaging: boxes of assorted flavors and sizes, without a count. Country: USA.

Who it is for: A 22,600 ppm xylitol varnish when the applicator detail you want is the dual-fiber brush and a natural-tooth dry shade.

Tradeoff: “Twice as many fibers” is the listing’s brush line, with no fiber count. Flavor names and a unit count are not printed, so none are added.

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9. MI Varnish — GC America

GC America MI Varnish is a 5% sodium fluoride varnish with Recaldent (CPP-ACP). The block says it releases fluoride, calcium, and phosphate, has a smooth creamy consistency, and is opaque white that dries clear. It names use with MI Paste and MI Paste Plus. The photo is a 50/pkg. The spec block says various unit sizes and flavors. Ppm is not printed. Country: USA.

Who it is for: A 5% NaF varnish when CPP-ACP is the added technology and the preventive system you already use includes the MI Paste products the listing names.

Tradeoff: The 50-count is the photo’s pack, and the spec still says the count varies. Ppm is not copied from the 22,600 ppm rows. “Higher” ion release is the listing’s word.

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10. Embrace Varnish — Pulpdent CXP

Pulpdent Embrace Varnish is a 5% sodium fluoride varnish at 22,600 ppm with CXP: xylitol-coated calcium and phosphate in a resin the listing says stays inactive until saliva dissolves the coating. The block says no mixing, no clumping, and a uniform dose, and it describes fluorapatite forming from those ions plus fluoride. Packaging: single-dose units or kits. Flavor is “pleasant,” not a named flavor. Country: USA.

Who it is for: A 22,600 ppm varnish when the calcium-phosphate story you want is CXP and the application is a single brush-on with no mix.

Tradeoff: The fluorapatite step and “sustained time-release” are the listing’s mechanism lines. A unit count and a wear time are not printed.