Table 1: Comparison of Top 5 Fluoride In-Office Products – Digits and NumbersProduct Name Fluoride Concentration Bottle Size (oz) Approximate Number of Treatments per Bottle Application Time (minutes) Oral-B® Minute-Foam® Topical Fluoride Foam 1.23% 5.8 120 N/A Gelato APF Gel 1.23% 16 100 1 Zooby® 1.23% APF Topical Fluoride Foam 1.23% 4.4 N/A N/A Kolorz® 60 Second Fluoride Foam 1.23% 4.4 N/A N/A DentiCare™ Pro-Rinse 2% N/A N/A 2
Table 2: Comparison of Top 5 Fluoride In-Office Products – Important Features
Product Name | Special Features | Recommended for | Flavor Options | Gluten-Free |
---|---|---|---|---|
Oral-B® Minute-Foam® Topical Fluoride Foam | Low pH for fast uptake, no trays required | N/A | N/A | N/A |
Gelato APF Gel | Thickens during treatment, creamy smooth gel, multiple flavor options | N/A | Multiple | N/A |
Zooby® 1.23% APF Topical Fluoride Foam | Matches Zooby prophy pastes, patient-friendly, easy to dispense | N/A | Multiple | N/A |
Kolorz® 60 Second Fluoride Foam | Sweetened with xylitol, free of gluten, aspartame, and saccharin | N/A | 4 | Yes |
DentiCare™ Pro-Rinse | No trays are required, and gentle neutral pH for cosmetic and porcelain restorations | Patients with cosmetic and porcelain restorations | N/A | N/A |
Top 10 Fluoride Trays for Dentists
1. Oral-B® Minute-Foam® Topical Fluoride Foam

Product Description
Oral-B® Minute-Foam® Topical Fluoride Foam is a professional-grade 1.23% APF (acidulated phosphate fluoride) foaming solution formulated for effective in-office fluoride treatments. With a low pH level, this foam promotes rapid fluoride uptake for enhanced enamel protection and caries prevention.
Product Overview
Designed for use with standard fluoride trays, each bottle of Minute-Foam® delivers approximately 120 full-mouth treatments. Its light, foaming consistency ensures optimal coverage with minimal product waste, making it ideal for quick and efficient application in both adult and pediatric patients.
Key Features
Contains 1.23% acidulated phosphate fluoride (APF)
Low pH enhances fluoride uptake and remineralization
Light foaming formula for even tray distribution
Delivers up to 120 full-mouth tray applications per bottle
Trusted Oral-B® quality for preventive care
Ideal for adult and pediatric fluoride treatments
Common Applications
In-office fluoride therapy for caries prevention
Post-cleaning fluoride application in hygiene appointments
Use in both pediatric and general dentistry
Support for remineralization of enamel in high-risk patients
Technical Specifications
Product Name: Oral-B® Minute-Foam® Topical Fluoride Foam
Brand: Oral-B®
Product Type: Topical Fluoride Foam
Fluoride Concentration: 1.23% APF
pH Level: Low pH for rapid uptake
Application Method: Tray-based delivery
Treatment Capacity: ~120 full-mouth applications per bottle
Use Case: In-office fluoride treatment
Package Quantity: 1 bottle
Country of Origin: USA
Customer Ratings
Rating: 4.9 out of 5 (Based on verified reviews)
Customer Feedback
Fast and effective fluoride delivery
Easy to apply with great patient tolerance
Excellent coverage with less product waste
A go-to fluoride foam in many dental practices
Top 10 Fluoride Varnishes for Dentistry
2. Gelato APF Gel – 1.23% fluoride by Keystone Industries

Product Description
Gelato APF Gel by Keystone Industries is a 1.23% acidulated phosphate fluoride (APF) gel designed for fast, effective, and patient-friendly fluoride treatments. With a creamy, smooth texture that thickens during use, this gel minimizes gagging and ensures optimal contact with tooth surfaces.
Product Overview
Formulated for rapid action in just 60 seconds, Gelato APF Gel delivers reliable fluoride protection while offering a pleasant experience with a variety of flavor options. The gel’s non-runny consistency and economical 16 oz bottle provide approximately 100 fluoride applications, making it a cost-effective solution for dental practices.
Key Features
Contains 1.23% APF for effective enamel protection
Smooth, creamy gel consistency that doesn’t run
Thickens during treatment to reduce gag reflex
Fast 60-second application
Available in multiple flavors for patient comfort
Delivers approximately 100 applications per 16 oz bottle
Economical and easy to use
Common Applications
In-office fluoride treatment for caries prevention
Use in both pediatric and adult patients
Post-prophylaxis fluoride application in hygiene appointments
Support for enamel remineralization and cavity prevention
Technical Specifications
Product Name: Gelato APF Gel – 1.23% Fluoride
Brand: Keystone Industries
Product Type: Topical Fluoride Gel
Fluoride Concentration: 1.23% APF
Application Time: 60 seconds
Consistency: Creamy, thickens during use
Flavor Options: Multiple available
Bottle Size: 16 oz (454 g)
Application Method: Tray-based delivery
Treatment Capacity: ~100 applications per bottle
Use Case: In-office fluoride treatment
Package Quantity: 1 bottle
Country of Origin: USA
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Patients love the flavors and smooth texture
Quick and easy fluoride delivery
Reduces gagging—especially in kids
Great value for high-volume practices
3. Zooby® 1.23% APF Topical Fluoride Foam

Product Description
Zooby® 1.23% APF Topical Fluoride Foam is a fun and flavorful fluoride treatment designed to inhibit the formation of dental caries in pediatric and adult patients. With a dense, mess-free formula and matching flavors to Zooby prophy pastes, it delivers a cohesive and enjoyable patient experience.
Product Overview
This professional-strength fluoride foam features 1.23% acidulated phosphate fluoride and is available in six appealing flavors to encourage compliance, especially among young patients. The thick consistency ensures even tray distribution without dripping, making it easy to apply and comfortable during treatment.
Key Features
Contains 1.23% acidulated phosphate fluoride (APF)
Helps prevent caries by strengthening enamel
Dense foam formula for mess-free, even application
Available in 6 kid-friendly flavors matching Zooby prophy pastes
Dispenses easily for quick setup and cleanup
Ideal for pediatric and general dental practices
Common Applications
In-office topical fluoride treatment for caries prevention
Post-cleaning fluoride therapy, especially for children
Moisture-controlled enamel strengthening in high-risk patients
Routine fluoride application during hygiene appointments
Technical Specifications
Product Name: Zooby® 1.23% APF Topical Fluoride Foam
Brand: Zooby®
Product Type: Topical Fluoride Foam
Fluoride Concentration: 1.23% APF
Consistency: Dense, non-drip foam
Flavor Options: 6 matching Zooby prophy paste flavors
Application Method: Tray-based delivery
Use Case: Caries prevention and enamel protection
Package Quantity: Varies by configuration
Country of Origin: USA
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Kids love the matching flavors
Easy to use with no mess
Great consistency—stays in place in trays
A fun and effective fluoride option for pediatric care
4. Kolorz® 60 Second Fluoride Foam by DMG-America

Product Description
Kolorz® 60 Second Fluoride Foam by DMG America is a fast-acting, xylitol-sweetened 1.23% APF topical fluoride foam designed to deliver effective enamel protection in just one minute. With a patient-friendly formula and clean ingredient profile, it supports caries prevention while offering a pleasant treatment experience.
Product Overview
This fluoride foam comes in four enjoyable flavors and is free from gluten, aspartame, and saccharin—making it an ideal choice for health-conscious patients and those with dietary sensitivities. The foam’s thick, stable consistency ensures even tray distribution and optimal contact with the teeth during the quick 60-second treatment.
Key Features
Contains 1.23% acidulated phosphate fluoride (APF)
Delivers effective treatment in just 60 seconds
Sweetened with xylitol for added patient appeal
Free from gluten, aspartame, and saccharin
Available in 4 great-tasting flavors
Stable, dense foam consistency for easy application
Common Applications
In-office fluoride treatment for caries prevention
Post-prophylaxis fluoride therapy
Ideal for patients with dietary restrictions or ingredient sensitivities
Routine hygiene appointments for both adults and children
Technical Specifications
Product Name: Kolorz® 60 Second Fluoride Foam
Brand: Kolorz® (DMG America)
Product Type: Topical Fluoride Foam
Fluoride Concentration: 1.23% APF
Application Time: 60 seconds
Sweetener: Xylitol
Free From: Gluten, aspartame, saccharin
Flavor Options: 4 flavors
Application Method: Tray-based delivery
Use Case: Fluoride therapy for enamel strengthening
Package Quantity: Varies by configuration
Country of Origin: USA
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Great flavor selection with no aftertaste
Safe for sensitive patients
Quick and easy to use
Reliable caries protection in a short time
5. DentiCare™ Pro-Rinse, 2% Neutral Sodium Fluoride Rinse

Product Description
DentiCare™ Pro-Rinse is a professional-strength 2% neutral sodium fluoride rinse formulated to provide effective fluoride treatment without the need for trays. It is especially recommended for patients with cosmetic or porcelain restorations due to its neutral pH, which is gentle on restorative materials.
Product Overview
Designed for convenience and comfort, this rinse requires only a two-minute application—performed as two 60-second rinses. Its neutral formula protects enamel and restorations while delivering effective caries prevention. Ideal for patients who prefer tray-free fluoride delivery or have sensitivity to acidic formulas.
Key Features
Contains 2% neutral sodium fluoride
Tray-free application—just rinse
Neutral pH is safe for porcelain and cosmetic restorations
Two-minute application (two 60-second rinses)
Comfortable and easy for patients to use
Effective enamel protection without acidic irritation
Common Applications
Fluoride therapy for patients with restorations or sensitivity
In-office or supervised at-home caries prevention
Post-cleaning fluoride application without trays
Support for patients with aesthetic restorations
Technical Specifications
Product Name: DentiCare™ Pro-Rinse, 2% Neutral Sodium Fluoride Rinse
Brand: DentiCare™
Product Type: Fluoride Rinse
Fluoride Concentration: 2% Neutral Sodium Fluoride
Application Method: Rinse (60 seconds x 2)
pH Level: Neutral (restoration-safe)
Use Case: Fluoride treatment for cosmetic/restorative patients
Tray Requirement: None
Package Quantity: Varies by configuration
Country of Origin: USA
Customer Ratings
Rating: 4.9 out of 5 (Based on verified reviews)
Customer Feedback
Perfect for patients with veneers or crowns
Easy and fast—no trays needed
Gentle formula with great fluoride benefits
Preferred by patients who dislike foam or gel trays
6. PCxx™ One Minute APF Gel by Ross Healthcare Inc

Product Description
PCxx™ One Minute APF Gel by Ross Healthcare Inc is a fast-acting, thixotropic fluoride gel designed for in-office use. With a 1.23% fluoride ion concentration and a pH of 3.5, it delivers effective enamel protection in just one minute, making it an efficient and patient-friendly choice for dental professionals.
Product Overview
This true thixotropic gel stays in place during treatment and reduces leak-back from the dental tray, ensuring a cleaner, more comfortable experience. Offered in natural flavors, the gel promotes patient compliance and acceptance. Each clear bottle provides approximately 80 applications and is gluten-free for added patient safety.
Key Features
1.23% fluoride ion concentration with 3.5 pH for effective caries prevention
One-minute application time for efficient treatment
True thixotropic formula reduces tray leak-back
Available in various natural flavors for better patient acceptance
Gluten-free and suitable for sensitive individuals
Approximately 80 applications per bottle
Clear bottle for easy monitoring of contents
Common Applications
Rapid in-office fluoride therapy for caries prevention
Post-cleaning fluoride treatment for children and adults
Comfortable fluoride application for sensitive patients
Support for enamel remineralization and acid resistance
Technical Specifications
Product Name: PCxx™ One Minute APF Gel
Brand: PCxx™
Manufacturer: Ross Healthcare Inc
Product Type: Topical Fluoride Gel
Fluoride Concentration: 1.23% APF
pH Level: 3.5
Application Time: 1 minute
Consistency: True thixotropic gel
Flavor Options: Natural flavor variants
Bottle Size: Clear bottle (application capacity ~80)
Use Case: In-office fluoride treatment
Reusability: Single-use per application
Package Quantity: 1 bottle
Gluten-Free: Yes
Country of Origin: USA
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Quick and easy to apply
Flavors are well-received by patients
No mess or tray overflow
Reliable protection with minimal chair time
7. DentiCare™ Pro-Gel 2% Neutral Sodium Fluoride

Product Description
DentiCare™ Pro-Gel 2% Neutral Sodium Fluoride is a gentle and effective in-office fluoride gel formulated for patients with composite or porcelain restorations. With a neutral pH, it helps protect enamel while minimizing the risk of dulling or etching aesthetic dental work.
Product Overview
This professional-strength gel offers a smooth, thixotropic consistency that stays in place during application, reducing the risk of overflow, gagging, or accidental ingestion. Designed for a standard 4-minute application, it’s ideal for patients with reduced salivary flow, acid sensitivity, or aesthetic restorations requiring non-acidic care.
Key Features
Contains 2% neutral sodium fluoride for gentle enamel protection
Neutral pH is safe for cosmetic restorations (composite/porcelain)
Smooth thixotropic gel consistency reduces gag risk and overflow
Ideal for patients with dry mouth or acid intolerance
4-minute in-office fluoride application
Comfortable and effective for a broad range of patient needs
Common Applications
Fluoride therapy for patients with cosmetic or porcelain restorations
Caries prevention for individuals with reduced salivary flow
Post-prophylaxis fluoride treatment in adult and pediatric patients
Safe, non-acidic fluoride option for sensitive patients
Technical Specifications
Product Name: DentiCare™ Pro-Gel 2% Neutral Sodium Fluoride
Brand: DentiCare™
Product Type: Topical Fluoride Gel
Fluoride Concentration: 2% Neutral Sodium Fluoride
pH Level: Neutral
Application Time: 4 minutes
Consistency: Smooth thixotropic gel
Use Case: Enamel protection, safe for restorations
Reusability: Single-use per application
Package Quantity: Varies by configuration
Country of Origin: USA
Customer Ratings
Rating: 4.9 out of 5 (Based on verified reviews)
Customer Feedback
Perfect for patients with veneers or composite work
Gentle and easy to apply
Stays in place—no mess or gagging
A reliable option for restorative and dry-mouth patients
8. Oral-B® Neutra-Foam® Fluoride Foaming Solution

Product Description
Oral-B® Neutra-Foam® is a topical neutral fluoride foaming solution specifically formulated for patients with crowns, bridges, glass-filled resin sealants, or complete restorations. Its neutral pH offers effective enamel protection while minimizing the risk of dulling or etching cosmetic dental work.
Product Overview
This foam provides superior coverage, especially in interproximal areas, while reducing the likelihood of overflow during tray application—helping to prevent accidental ingestion. Neutra-Foam® is also ideal for patients with reduced salivary flow or sensitivity to acidic fluoride products.
Key Features
Neutral pH protects cosmetic restorations from etching or dulling
Foam consistency ensures excellent interproximal coverage
Less overflow during application minimizes risk of ingestion
Suitable for patients with crowns, bridges, and sealants
An ideal alternative to acidic fluoride for sensitive patients
Trusted Oral-B® quality for restorative-friendly fluoride care
Common Applications
Topical fluoride treatment for patients with dental restorations
Use in cases of reduced salivary flow or fluoride sensitivity
Post-cleaning fluoride therapy in hygiene visits
Protection of enamel and restorations in general dental care
Technical Specifications
Product Name: Oral-B® Neutra-Foam® Fluoride Foaming Solution
Brand: Oral-B®
Product Type: Neutral Fluoride Foam
Fluoride Concentration: Not specified (neutral sodium fluoride formulation)
pH Level: Neutral
Application Method: Tray-based delivery
Consistency: Foam
Use Case: Fluoride protection for restorative and sensitive patients
Reusability: Single-use per application
Package Quantity: Varies by configuration
Country of Origin: USA
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Perfect for patients with crowns and bridges
Foam stays in place and is comfortable
Great for sensitive mouths or those with dry mouth
Highly effective without affecting restorations
9. Topex® 60 Second Fluoride Foam by Sultan Healthcare Inc

Product Description
Topex® 60 Second Fluoride Foam by Sultan Healthcare is a professional 1.23% acidulated phosphate fluoride (APF) topical solution formulated to enhance fluoride uptake in enamel. With a 3.5 pH and 12,300 ppm fluoride concentration, it delivers effective caries prevention in just one minute.
Product Overview
This dense foam is engineered to stay in place under bite pressure, reducing the risk of gagging or ingestion during tray application. Each 4.4 oz (132 ml) bottle provides approximately 110 full-mouth treatments, making it an efficient and economical choice for routine in-office fluoride care.
Key Features
1.23% APF with 12,300 ppm fluoride concentration
3.5 pH promotes rapid fluoride absorption into enamel
Dense foam stays in place under bite pressure
Reduces risk of gagging or swallowing the product
Quick 60-second application time
Provides approximately 110 applications per 4.4 oz bottle
Common Applications
In-office fluoride therapy for caries prevention
Post-cleaning fluoride application in hygiene visits
Treatment for pediatric and adult patients requiring enamel strengthening
Routine topical fluoride use in general dental practices
Technical Specifications
Product Name: Topex® 60 Second Fluoride Foam
Brand: Topex®
Manufacturer: Sultan Healthcare Inc
Product Type: Topical Fluoride Foam
Fluoride Concentration: 1.23% APF (12,300 ppm)
pH Level: 3.5
Application Time: 60 seconds
Consistency: Dense foam
Bottle Size: 4.4 oz (132 ml)
Treatment Capacity: ~110 applications per bottle
Use Case: Fluoride therapy for caries prevention
Reusability: Single-use per application
Package Quantity: 1 bottle
Country of Origin: USA
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Foam consistency is perfect—no mess or gagging
Quick and effective application
Patients like the taste and feel
Reliable results with high fluoride uptake
10. PCxx™ 2.0% Sodium Fluoride Neutral Gel

Product Description
PCxx™ 2.0% Sodium Fluoride Neutral Gel is a professional topical fluoride treatment formulated with a neutral pH to ensure compatibility with composite and porcelain restorations. It provides effective enamel protection without the risk of etching or dulling cosmetic dental work.
Product Overview
This thixotropic gel thickens during application to minimize leak-back from trays and reduce the risk of gagging or ingestion. With approximately 80 applications per bottle and a selection of 7 natural flavors, PCxx™ Neutral Gel offers both clinical reliability and improved patient acceptance.
Key Features
2.0% sodium fluoride concentration for effective caries prevention
Neutral pH safe for cosmetic restorations (composite and porcelain)
Thixotropic formula reduces tray overflow and discomfort
Available in 7 natural flavors for better patient compliance
Approximately 80 applications per bottle
Comfortable and effective for a wide range of patients
Common Applications
Fluoride therapy for patients with cosmetic dental restorations
Caries prevention in individuals with sensitivity to acidic treatments
Post-prophylaxis fluoride treatment for adults and children
Routine in-office enamel protection
Technical Specifications
Product Name: PCxx™ 2.0% Sodium Fluoride Neutral Gel
Brand: PCxx™
Product Type: Topical Fluoride Gel
Fluoride Concentration: 2.0% Sodium Fluoride
pH Level: Neutral
Application Time: Standard (typically 4 minutes)
Consistency: Thixotropic gel
Flavor Options: 7 natural flavors
Application Method: Tray-based delivery
Treatment Capacity: ~80 applications per bottle
Use Case: Enamel protection for restorative patients
Reusability: Single-use per application
Package Quantity: 1 bottle
Country of Origin: USA
Customer Ratings
Rating: 4.9 out of 5 (Based on verified reviews)
Customer Feedback
Excellent option for patients with restorations
No irritation or mess—very clean application
Patients like the natural flavors
Reliable fluoride delivery with easy handling