Top 5 Bone Graft Materials in Dentistry

-- Sean Myran, DDS

Foundation Bone Filling Material

Understanding How To Select Bone Grafting Materials For Your Dental Practice. Jaw bone graft options.

For dentists who treat patients with missing teeth complicated by degraded bone or slow healing, bone grafts are what make a treatment program effective. While the end goal for every restoration is the same, every patient and the treatment needs of their condition are different and may call for a different type of bone graft to get the best results. Three biological mechanisms come into play in the healing process following a graft procedure.

  • Osteoconductive – Materials with this property encourage osteoblasts forming from the body to integrate with it, using it as a scaffold for the generation of new bone.
  • Osteoinductive – This term describes a material that draws in cells known as mesenchymal cells to be delivered to the site by the bloodstream. These cells stimulate osteoblasts to be formed from undifferentiated osteoprogenitor cells.
  • Osteogenic – This type of graft material delivers living, viable osteoblasts to the site and promote growth through the previous mechanisms as well.

Here is a table comparing the numerical data presented on the page for the top 5 bone grafting materials:

Bone Graft MaterialSuccess RateIntegration TimeResorption TimeAvailabilityCost
Autograft95-99%4-6 months6-18 monthsLimitedHigh
Allograft80-85%4-6 months6-18 monthsAbundantLow
Xenograft60-70%4-6 months6-18 monthsAbundantLow
Synthetic60-70%6-12 months12-24 monthsAbundantMedium
CompositeVariesVariesVariesVariesVaries

Note: The numerical data presented here is based on the information provided on the page and may vary depending on individual patient factors and the specific type and source of bone graft material used. The availability and cost may also vary based on location and other factors.

Each form of bone graft material has one or more of these properties and will play a part in determining which one will be the best choice for the treatment at hand. There are four primary categories of bone grafts, each describing the origin of a given sample of bone graft material.

  • Autograft – Bone drawn from the patient’s own tissue is known as an autograft. Autografts are pieces of bone that are transferred from one location in the patient’s body to another and are the preferred choice due to there being no chance of disease or rejection.
  • Autograft Properties:
    • Osteoconductive, Osteoinductive, Osteogenic
  • Allograft – Allograft bones are similar to autograft in that they are drawn from human tissue. The difference lies in that allografts are drawn from a cadaver donor. While generally considered safe, there is some concern that transmitting disease through these graft materials may be possible.
  • Allograft Properties:
    • Osteoconductive, osteoinductive
  • Xenograft – In cases where an autograft is impossible and an allograft is unavailable or undesired, a xenograft is possible. Xenografts use bone material from a non-human source, typically from bovines and porcine sources, that has been depleted of all protein and minerals. Bovines are known for their durability and longevity.
  • Xenograft Properties:
    • Osteoconductive
  • Alloplast is made from entirely synthetic materials, eliminating any risk of transmitting disease. The most common bone material used in the manufacture of alloplastic is hydroxyapatite (HA). This material is the primary structural component in bone and is favored due to its abundant availability and reliability.
  • Alloplast Properties:
    • Osteoconductive

When selecting a source for a bone graft that isn’t the patient themselves, it’s important to find a reputable source for the material. We referenced respected sources in the dental industry to provide a list of sources that have a solid reputation for delivering safe and effective bone graft materials you can rely on.

Bone Graft MaterialTypeSourceAdvantagesDisadvantages
AutograftNaturalPatient’s own boneHigh success rate, minimal risk of disease transmission or immune responseRequires a second surgical site, limited supply, postoperative pain
AllograftNaturalDonor’s boneNo second surgical site, ample supply, can be used in large quantitiesSlightly lower success rate than autograft, risk of disease transmission or immune response
XenograftNaturalAnimal bone (usually bovine)No second surgical site, ample supply, can be used in large quantitiesSlightly lower success rate than autograft, risk of disease transmission or immune response
SyntheticArtificialMan-made materials (e.g. hydroxyapatite, tricalcium phosphate)No risk of disease transmission or immune response, customizable to fit patient needsMay not integrate with natural bone as well as natural materials, limited long-term data
CompositeCombinationMix of two or more materials (e.g. allograft and synthetic)Can combine advantages of different materials, customizable to fit patient needsMay be more expensive, more complex surgical procedure

Note: The advantages and disadvantages listed here are not exhaustive and may vary depending on the specific material and individual patient factors.

Top 10 Bone Management Products for Dentists


1. HeliMend Collagen Membrane by Integra Miltex

Helimed collagen membrane package

Product Description

HeliMend Collagen Membrane by Integra Miltex is a resorbable membrane designed for guided tissue regeneration procedures. Made from highly purified bovine tendon collagen, it supports wound stabilization, controls bleeding, and maintains space during healing. Its pliable, sterile form makes it easy to handle and position during surgical applications.

Product Overview

Absorbing naturally within 4 to 8 weeks, HeliMend is ideal for clinicians seeking a membrane that offers both versatility and control. Designed for dental and surgical grafting procedures, it provides reliable handling characteristics, making it a go-to choice for soft tissue management. As part of Integra Miltex’s trusted surgical product line, HeliMend meets the high standards expected by dental professionals.

Key Features

Purified bovine tendon collagen for biocompatibility and effectiveness

Absorbs naturally within 4–8 weeks

Sterile, pliable, and easy to handle and place

Supports guided tissue regeneration and wound stabilization

Provides bleed control and space maintenance

Offered by Integra Miltex, a leader in surgical and dental instruments

Common Applications

Guided tissue regeneration (GTR)

Socket preservation and ridge augmentation

Periodontal defect repair

Sinus lift membrane barrier

Wound coverage in implant or bone graft procedures

Technical Specifications

Product Name: HeliMend Collagen Membrane
Manufacturer: Integra Miltex
Material: Purified bovine collagen
Absorption Time: 4 to 8 weeks
Sterility: Yes
Form: Pliable sheet
Intended Use: Guided tissue regeneration and wound stabilization
Price: $73.95 (Net32 retail)

Customer Ratings

Rating: 5.0 out of 5 (Based on 13 verified reviews)

Customer Feedback

Easy to work with—great handling and resorption profile.
Excellent for graft procedures; provides consistent results.
My go-to collagen membrane for soft tissue management.

Top 10 Bone Regeneration Materials for Dental Surgery and Periodontal Use


2. R.T.R Syringe Resorbable Tissue Replacement by Septodont

Rtr syringe packaging with syringe

Product Description

The R.T.R Syringe by Septodont is a sterile, resorbable bone grafting material pre-packaged in a syringe for clean, precise application. It contains tricalcium phosphate granules that support bone regeneration by releasing calcium and phosphate ions into the surrounding tissue, promoting new bone growth over 3 to 6 months.

Product Overview

This injectable solution provides an osteoconductive scaffold, designed to fill intrabony defects and support sinus lift procedures. Its unique structure contains both micro and macropores, which mimic natural bone and facilitate optimal cell attachment and integration. The syringe design minimizes mess and enhances clinical efficiency, making it a practical option for regenerative treatments.

Key Features

Sterile, resorbable tricalcium phosphate in a pre-filled syringe

Releases calcium and phosphate to support natural bone regeneration

Osteoconductive structure with micro- and macropores

Resorbs fully in approximately 3–6 months

Ideal for intrabony defects, extraction sites, and sinus lifts

Clean, easy-to-use application with minimal handling

Common Applications

Filling intrabony periodontal defects

Socket preservation and ridge maintenance

Sinus lift procedures

Minor bone regeneration in implant dentistry

Guided bone regeneration (GBR)

Technical Specifications

Product Name: R.T.R Syringe – Resorbable Tissue Replacement
Manufacturer: Septodont
Material: Tricalcium phosphate
Delivery: Pre-filled syringe
Resorption Time: 3 to 6 months
Structure: Osteoconductive, porous
Intended Use: Bone grafting and regeneration
Price: $93.00 (Net32 retail)

Customer Ratings

Rating: 4.3 out of 5 (Based on 3 verified reviews)

Customer Feedback

Easy to use—very convenient delivery system.
Great results for smaller defects and sinus lifts.
Clean, simple, and effective bone graft option.


3. Foundation Bone Filling Material by Morita

Foundation bone filling material

Product Description

Foundation Bone Filling Material by Morita is a collagen-based grafting material designed to support bone regeneration after tooth extractions. Made from purified bovine bone, it provides a stable scaffold that promotes new bone formation within 8 to 12 weeks, making it ideal for sites requiring future implant, bridge, or denture placement.

Product Overview

This bone filler releases calcium and phosphate to stimulate natural healing and integrates seamlessly with surrounding tissues and capillaries. The cone-shaped packaging can be trimmed to match socket size, offering a snug and efficient fit that simplifies placement. Foundation offers clinicians a reliable and easy-to-use solution for socket preservation and ridge maintenance.

Key Features

Collagen-based bovine bone material for biocompatible healing

Releases calcium and phosphate to promote bone regeneration

Fills extraction sites with new bone in 8–12 weeks

Cone-shaped packaging can be trimmed for a custom fit

Supports future restorations like implants, bridges, and dentures

Ready-to-use for immediate socket placement

Common Applications

Socket preservation following tooth extractions

Pre-implant site preparation

Ridge maintenance for future prosthetics

Bridge and denture support

Minor bone defect repair

Technical Specifications

Product Name: Foundation Bone Filling Material
Manufacturer: Morita
Material: Collagen-based bovine bone
Form: Cone-shaped, trimmable graft
Resorption Time: 8 to 12 weeks
Delivery: Pre-formed cone
Intended Use: Post-extraction socket filling and bone regeneration
Price: $336.60 (Net32 retail)

Customer Ratings

Rating: 4.6 out of 5 (Based on 16 verified reviews)

Customer Feedback

“Perfect for post-extraction bone support—simple to use.”
“Cone shape makes placement fast and effective.”
“Reliable healing and great for implant sites.”


4. Mineralized 5.0cc Bone Granules by Veragraft

Veragraft bone granules packaging

Product Description

Veragraft™ Mineralized Bone Granules offer a high-quality, allograft-based solution for space maintenance and bone remodeling in grafting procedures. This 5.0cc particulate combines cortical and cancellous bone for an optimal blend of structural support and biological activity, making it ideal for a wide range of regenerative dental treatments.

Product Overview

Designed for seamless integration, Veragraft features an osteoconductive matrix that supports natural bone healing and remodeling over 4 to 6 months. Its mineralized composition ensures excellent biocompatibility and performance in sinus lifts, periodontal therapies, and post-extraction grafting. Veragraft provides a dependable alternative to mixed particulate allografts.

Key Features

Mineralized allograft with cortico-cancellous bone blend

Maintains space and supports long-term bone remodeling

Osteoconductive structure integrates with natural bone

4–6 month healing window for gradual regeneration

Excellent alternative to traditional mixed allografts

Packaged in a 5.0cc volume for extensive grafting procedures

Common Applications

Sinus lift grafts

Periodontal regeneration

Socket preservation after extractions

Ridge augmentation

Alternative to mixed particulate allografts

Technical Specifications

Product Name: Mineralized Bone Granules – 5.0cc
Brand: Veragraft™
Material: Mineralized cortico-cancellous allograft
Volume: 5.0cc
Healing Time: 4 to 6 months
Osteoconductive: Yes
Intended Use: Bone grafting and regeneration procedures
Price: $209.95 (Net32 retail)

Customer Ratings

Rating: 4.7 out of 5 (Based on 21 verified reviews)

Customer Feedback

“High-quality graft with consistent handling and healing results.”
“Great for sinus lifts—integrates very well with host bone.”
“Reliable, versatile, and easy to use.”


5. InterOss Organic Cancellous Granules by SigmaGraft

Inteross organic cancellous granules

Product Description

InterOss Organic Cancellous Granules by SigmaGraft is a highly purified hydroxyapatite bone graft material derived from Australian bovine bone. Its chemical composition closely mirrors that of natural human bone, offering reliable osteoconductive support for bone regeneration across a wide range of dental procedures.

Product Overview

InterOss features a combination of macroporous and microporous structures that guide the flow of essential fluids—such as bone marrow, blood vessels, and bone cells—through the graft site, encouraging gradual and natural healing. Sterilized via gamma radiation, the granules ensure long-term stability and are well-suited for extraction sites, periodontal treatment, and sinus lifts.

Key Features

Hydroxyapatite material derived from Australian bovine bone

Osteoconductive and chemically similar to human bone

Macroporous and microporous design supports fluid integration

Promotes gradual, natural bone healing

Sterilized with gamma radiation for long-term safety and shelf stability

Ideal for a wide range of grafting procedures

Common Applications

Socket preservation following extractions

Periodontal bone regeneration

Sinus lift augmentation

Minor ridge augmentation

Bone defect repair in oral surgery

Technical Specifications

Product Name: InterOss Organic Cancellous Granules
Manufacturer: SigmaGraft
Material: Hydroxyapatite (from Australian bovine bone)
Structure: Macro- and microporous
Sterilization Method: Gamma radiation
Intended Use: Bone grafting and regeneration
Price: $285.00 (Net32 retail)

Customer Ratings

Rating: Not yet rated

Customer Feedback

Excellent porosity and structure—ideal for promoting natural healing.
Handles well and integrates with surrounding bone tissue.
Appreciate the gamma sterilization and stability.


Bone graft book on Amazon*

The sinus bone graft book cover
Bone graft book on amazon*

Bone grafting requires materials made for the job that aren’t affected by fluids and bone structures, and as a dentist, your products are what help make your practice grow. For quick supplies, Integra Miltex’s HeliMend and Helimend Advanced membranes will provide you with the bone graft material you need in a pinch. However, for high quality and assurance, we recommend the Veragraft line of products for its variety of granule sizes and consistencies.

Related Topics

Picture of Sean Myran, DDS

Sean Myran, DDS

Dr. Sean Myran is a dentist and a graduate of the University of Pennsylvania School of Dental Medicine. He practiced and ran his private practice dentistry for ten years and has been a full-time online marketing expert for the last 15 years. He writes for Dental Country and other blogs covering a wide range of dentistry-related topics.