Home › Guides › Top 10 Bone Regeneration Materials for Dental Surgery and Periodontal Use
Comparison Table for Bone Regeneration Materials
Brand and Product Name Packaging Sterility Absorption Rate Ideal Use HealiAid Collagen Plug by Surgical Esthetics Individually packaged Sterile N/A Bone graft covering or socket filler OSSIF-i sem™ Mineralized Cortical-Cancellous Bone Allograft SP by Surgical Esthetics Double-sterile pack Sterile N/A Elevation of maxillary sinus, ridge augmentation, large extraction sockets, and volume maintenance OSSIF-i sem™ Demineralized Cortical Bone Allograft by Surgical Esthetics Double-sterile pack Sterile N/A Treatment of periodontal defects, filling of extraction sockets, and composite grafting HeliMend Collagen Membrane – Miltex by Integra N/A N/A 4-8 weeks Guided tissue regeneration procedures OSSIF-i sem™ Mineralized Cancellous Bone Allograft by Surgical Esthetics Double-sterile jar Sterile N/A Ridge augmentation before implant placement, periodontal defects, filling of extraction sockets, and elevation of maxillary sinus Foundation™ Bone Filling Material by J Morita USA Individually packaged in a sterile container Sterile N/A Filling extraction sockets after teeth extractions to provide support for implants, bridges, and dentures R.T.R. Membrane by Septodont Inc N/A N/A N/A Compatible with RTR bone regeneration products CollaShield™ Collagen Membrane by Surgical Esthetics Double-sterile pack Sterile N/A Guided bone and tissue regeneration HeliMend Advanced Collagen Membrane by Miltex by Integra in the form of a collagen membrane Sterile 18 weeks It is used during guided tissue regeneration procedures where a longer absorption rate is desired. R.T.R.+ Synthetic Biphasic Bone Grafting Substitute Syringe by Septodont Inc syringe form with a volume of 0.5 cc. Sterile The absorption rate depends on the composition It is used for reconstructing bone gaps or bony loss in maxillofacial applications
Top 10 Bone Management Products for Dentists
1. HealiAid Collagen Plug by Surgical Esthetics Product Description HealiAid Collagen Plug by Surgical Esthetics is a sterile, absorbable collagen wound dressing designed for effective socket management and graft site protection. Its porous and pliable structure makes it easy to shape, cut, and apply to various surgical sites.
Product Overview Ideal for use as a socket filler or bone graft covering, the HealiAid Collagen Plug supports wound healing by stabilizing clots and protecting exposed sites. Each plug is individually packaged, sterile, and intended for single use. Its nonpyrogenic packaging ensures safety and compliance in clinical settings.
Key Features
Porous, absorbable collagen structure for optimal healing
Pliable and easy to cut or mold to fit site-specific needs
Ideal for use as socket filler or graft covering
Sterile and individually packaged for infection control
Single-use only
Nonpyrogenic packaging for added safety
Common Applications
Post-extraction socket management
Coverage for bone grafts and surgical sites
Periodontal and implant procedures requiring wound stabilization
Technical Specifications
Product Type: Absorbable collagen wound dressing
Sterility: Sterile
Packaging: Individually packaged
Use: Single-use only
Material: Porous collagen
Manufacturer: Surgical Esthetics
Packaging Type: Nonpyrogenic
Customer Ratings Average Rating: 4.8 out of 5 (based on clinical feedback)
Customer Feedback
Easy to shape and place
Excellent for clot stabilization and site protection
Reliable healing aid in grafting and extraction procedures
High quality and convenient individual packaging
2. OSSIF-i sem™ Mineralized Cortical-Cancellous Bone Allograft SP by Surgical Esthetics Product Description OSSIF-i sem™ Mineralized Cortical-Cancellous Bone Allograft SP by Surgical Esthetics is a high-quality bone graft material designed for predictable bone regeneration. This allograft combines both cortical and cancellous components to support volume stability and rapid integration in a wide range of dental surgical applications.
Product Overview Processed to ensure safety and biocompatibility, OSSIF-i sem™ SP offers an ideal balance of structure and porosity. The cortical component provides long-term support and space maintenance, while the cancellous matrix promotes vascular infiltration and bone remodeling. It is supplied sterile and ready for immediate clinical use.
Key Features
Combination of mineralized cortical and cancellous bone
Enhances space maintenance and bone volume stability
Promotes angiogenesis and osteoconduction
Sterile and ready-to-use
Suitable for ridge preservation, sinus lifts, and socket grafting
Common Applications
Ridge preservation after extractions
Periodontal defect repair
Sinus augmentation procedures
Implant site development and socket grafting
Technical Specifications
Product Type: Bone allograft
Composition: Mineralized cortical-cancellous blend
Sterility: Sterile
Use: Single-use, ready-to-use
Manufacturer: Surgical Esthetics
Packaging: SP (premeasured, sterile packaging)
Customer Ratings Average Rating: 4.9 out of 5 (based on professional feedback)
Customer Feedback
Excellent handling and graft stability
Consistently high-quality results
Great for both large and small defect repairs
Trusted material for implant site preparation
3. OSSIF-i sem™ Demineralized Cortical Bone Allograft by Surgical Esthetics Product Description OSSIF-i sem™ Demineralized Cortical Bone Allograft by Surgical Esthetics is an advanced grafting material designed for regenerative dentistry and socket preservation. Featuring 0.25–1 mm particle size, this demineralized bone matrix provides both osteoinductive and osteoconductive properties to promote reliable bone regeneration.
Product Overview Packaged in a double-sterile jar for direct transfer to the surgical field, OSSIF-i sem™ offers excellent handling once hydrated. It is ideal for periodontal defects, socket grafting, and use with implants. Each lot is tested for inductivity to ensure consistent clinical performance and biologic activity.
Key Features
Demineralized cortical bone with 0.25–1 mm particle size
Proven osteoinductive and osteoconductive properties
Excellent handling characteristics upon hydration
Packaged in double-sterile jars for direct sterile field use
Lot-tested for inductivity and clinical consistency
Common Applications
Periodontal defect treatment
Extraction socket grafting
Grafting in conjunction with implant placement
Composite grafting with other OSSIF-i sem™ products
Technical Specifications
Product Type: Demineralized cortical bone allograft
Particle Size: 0.25–1 mm
Sterility: Double-sterile packaging
Use: Ready-to-use upon hydration
Manufacturer: Surgical Esthetics
Testing: Lot tested for inductivity
Customer Ratings Average Rating: 4.9 out of 5 (based on clinician feedback)
Customer Feedback
Excellent handling and adaptability to site
Trusted for consistent bone regeneration
Convenient sterile packaging for surgical environments
Strong results in both socket and implant grafting cases
4. HeliMend Collagen Membrane – Miltex by Integra Product Description HeliMend™ Collagen Membrane by Miltex (Integra) is an absorbable membrane made from purified bovine tendon, designed to support guided tissue regeneration (GTR) and guided bone regeneration (GBR) procedures. It offers structural integrity and biocompatibility, making it ideal for wound stabilization and space maintenance.
Product Overview HeliMend is engineered to provide a longer resorption time of 4–8 weeks, allowing for extended barrier function during healing. Its natural collagen composition is easily handled, pliable when hydrated, and conforms well to grafted sites. It resorbs naturally without the need for surgical removal.
Key Features
Made from purified bovine tendon
Absorbable in 4–8 weeks
Maintains space and stabilizes wounds for GTR and GBR
Biocompatible and pliable for easy placement
No need for surgical removal
Common Applications
Guided tissue regeneration (GTR)
Guided bone regeneration (GBR)
Socket preservation and ridge augmentation
Periodontal and peri-implant defect coverage
Technical Specifications
Product Type: Absorbable collagen membrane
Material: Purified bovine tendon
Absorption Time: 4–8 weeks
Sterility: Sterile
Manufacturer: Miltex by Integra
Customer Ratings Average Rating: 4.8 out of 5 (based on professional feedback)
Customer Feedback
Excellent handling and conformability
Reliable barrier during extended healing periods
Resorbs predictably without complications
Preferred for regenerative procedures
5. OSSIF-i sem™ Mineralized Cancellous Bone Allograft by Surgical Esthetics Product Description OSSIF-i sem™ Mineralized Cancellous Bone Allograft by Surgical Esthetics is a porous, osteoconductive grafting material designed to promote complete bone regeneration. Its structure and particle composition provide optimal support for natural bone remodeling and space maintenance during healing.
Product Overview Formulated for maximum esthetics and biological integration, OSSIF-i sem™ Mineralized Cancellous Bone supports host bone in-growth and provides an ideal scaffold for new bone formation. Its excellent space-maintaining properties make it suitable for a wide range of surgical and regenerative procedures.
Key Features
Osteoconductive matrix encourages bone regeneration
Porous structure supports host bone in-growth
Ideal particle mix for handling and packing
Provides space maintenance for optimal esthetic outcomes
Promotes osseous integration and natural bone remodeling
Common Applications
Ridge augmentation prior to implant placement
Grafting in conjunction with implant surgeries
Filling periodontal and osseous defects
Extraction socket preservation
Maxillary sinus elevation procedures
Technical Specifications
Product Type: Mineralized cancellous bone allograft
Properties: Osteoconductive, porous architecture
Packaging: Sterile, ready-to-use
Manufacturer: Surgical Esthetics
Customer Ratings Average Rating: 4.9 out of 5 (based on clinical feedback)
Customer Feedback
Excellent space maintenance and graft stability
Easy to handle and pack
Predictable healing and remodeling outcomes
Ideal for implant and ridge development procedures
Top 5 Bone Graft Materials in Dentistry
6. Foundation™ Bone Filling Material by J Morita USA Product Description Foundation™ Bone Filling Material by J. Morita USA is a collagen-based augmentation material specifically designed to fill extraction sockets and support bone regeneration following tooth extractions. Its unique shape and handling properties make it easy to place and adapt to a variety of clinical situations.
Product Overview Foundation™ promotes rapid bone growth, allowing for implant placement as early as 8–12 weeks post-extraction. Shaped like a bullet for simplified insertion, it can also be trimmed or contoured for an optimal fit in the socket. Each unit is individually packaged in a sterile container for convenience and infection control.
Key Features
Collagen-based bone filling material
Bullet-shaped for easy and secure placement
Can be trimmed or shaped to fit specific sites
Promotes accelerated bone growth and healing
Suitable for implants, bridges, and denture support
Individually packaged in sterile containers
Common Applications
Filling extraction sockets
Site preparation for implants, bridges, or dentures
Post-extraction grafting to maintain ridge contour
Technical Specifications
Product Type: Bone filling augmentation material
Material: Collagen-based
Shape: Bullet (trim-to-fit)
Sterility: Individually packaged, sterile
Healing Timeline: Implant placement possible in 8–12 weeks
Manufacturer: J. Morita USA
Customer Ratings Average Rating: 4.8 out of 5 (based on clinical feedback)
Customer Feedback
Easy to place and shape
Speeds up bone regeneration
Convenient sterile packaging
Effective for implant and prosthetic site preparation
7. R.T.R. Membrane by Septodont Inc Product Description R.T.R. Membrane by Septodont is a resorbable collagen membrane designed to support guided bone and tissue regeneration. Made from bovine collagen, it offers flexibility, strength, and easy adaptability to surgical sites, making it ideal for use with R.T.R. bone regeneration products.
Product Overview This membrane can be easily trimmed to fit a variety of grafting sites and contours well to both hard and soft tissues. Its tear-resistant properties ensure stability during placement, while maintaining the barrier function required for predictable regenerative outcomes.
Key Features
Made from biocompatible bovine collagen
Tear-resistant yet flexible for easy handling
Easily cut to size for site-specific applications
Designed for use with R.T.R. bone regeneration products
Maintains space and stabilizes the graft during healing
Common Applications
Guided bone regeneration (GBR)
Guided tissue regeneration (GTR)
Socket preservation and ridge augmentation
Use in conjunction with bone grafts, especially R.T.R. products
Technical Specifications
Product Type: Resorbable collagen membrane
Material: Bovine collagen
Features: Flexible, tear-resistant, cut-to-fit
Compatibility: R.T.R. bone regeneration products
Manufacturer: Septodont Inc.
Customer Ratings Average Rating: 4.7 out of 5 (based on clinical feedback)
Customer Feedback
Easy to place and adapt
Holds up well during suturing
Excellent compatibility with bone grafts
Trusted for reliable healing outcomes
8. CollaShield™ Collagen Membrane by Surgical Esthetics Product Description CollaShield™ Collagen Membrane by Surgical Esthetics is a fully resorbable, cell-occlusive membrane designed to support osteogenesis and protect graft sites during healing. Ideal for socket preservation, guided bone regeneration (GBR), and guided tissue regeneration (GTR), it provides structural integrity and biological compatibility.
Product Overview Constructed from purified porcine peritoneum, CollaShield™ is engineered to inhibit unwanted cellular growth while maintaining the ideal environment for bone regeneration. The membrane resorbs naturally in approximately 16 weeks and can be easily trimmed to adapt to various clinical applications.
Key Features
Fully resorbable in approximately 16 weeks
Made from purified porcine peritoneum
Cell-occlusive to inhibit epithelial cell migration
Supports osteogenesis and graft site stability
Easily trimmed to fit site-specific needs
Common Applications
Extraction socket preservation
Guided bone regeneration (GBR)
Guided tissue regeneration (GTR)
Graft site protection in periodontal and implant procedures
Technical Specifications
Product Type: Resorbable collagen membrane
Material: Purified porcine peritoneum
Resorption Time: ~16 weeks
Structure: Cell-occlusive
Trimmable: Yes
Manufacturer: Surgical Esthetics
Customer Ratings Average Rating: 4.9 out of 5 (based on clinical feedback)
Customer Feedback
Excellent for maintaining graft stability
Easy to handle and contour
Predictable resorption and healing support
Trusted in both periodontal and implant surgeries
9. HeliMend Advanced Collagen Membrane by Miltex by Integra Product Description HeliMend™ Advanced Collagen Membrane by Miltex (Integra) is a long-lasting, absorbable membrane made from purified bovine tendon. It is designed to support guided tissue regeneration (GTR) by stabilizing wounds and maintaining space during healing in complex procedures requiring extended resorption time.
Product Overview With an absorption period of approximately 18 weeks, HeliMend™ Advanced offers extended barrier function to support optimal tissue and bone regeneration. Its pliable form adapts easily to graft sites while maintaining mechanical integrity for predictable clinical outcomes.
Key Features
Made from purified bovine tendon
Long resorption time: approximately 18 weeks
Stabilizes wound and maintains space during healing
Ideal for guided tissue and bone regeneration procedures
Fully absorbable—no need for surgical removal
Common Applications
Guided tissue regeneration (GTR)
Guided bone regeneration (GBR)
Socket preservation and ridge augmentation
Periodontal and peri-implant defect coverage
Technical Specifications
Product Type: Absorbable collagen membrane
Material: Purified bovine tendon
Absorption Time: ~18 weeks
Sterility: Sterile
Manufacturer: Miltex by Integra
Customer Ratings Average Rating: 4.8 out of 5 (based on professional feedback)
Customer Feedback
Excellent strength and handling
Reliable for extended regenerative procedures
Predictable resorption profile
Highly effective in maintaining space for healing
10. R.T.R.+ Synthetic Biphasic Bone Grafting Substitute Syringe by Septodont Inc Product Description R.T.R.+ Synthetic Biphasic Bone Grafting Substitute Syringe by Septodont Inc is a fully absorbable, sterile grafting material engineered for maxillofacial bone regeneration. Formulated with a biphasic combination of ß-Tricalcium Phosphate (ß-TCP) and Hydroxyapatite (HA), it supports effective bone healing and structural restoration across a wide range of surgical applications.
Product Overview R.T.R.+ is offered in two biphasic ratios—40/60 and 80/20—to match specific clinical timelines for resorption and bone remodeling. Its micro- and macroporous structure enhances cellular colonization and vascular in-growth, while the osteoconductive composition creates a strong matrix for guided bone formation.
Key Features
Synthetic, sterile, and fully absorbable biphasic formula
Combines ß-Tricalcium Phosphate (bioactive) with Hydroxyapatite (stable)
Micro-/macroporous architecture promotes cellular in-growth
Osteoconductive matrix ideal for strong, guided bone regrowth
Supplied in a ready-to-use syringe for easy handling and application
Two resorption profiles:
40/60 (40% ß-TCP / 60% HA): Bone formation in 3–9 months80/20 (80% ß-TCP / 20% HA): Bone formation in 9–12 months
Common Applications
Post-extraction socket grafting
Sinus lifts and ridge augmentations
Cystic cavity fillings
Periodontal and peri-implant defect repair
Intraosseous and maxillofacial reconstruction
Technical Specifications
Product Type: Synthetic biphasic bone graft substitute
Composition: ß-Tricalcium Phosphate and Hydroxyapatite
Forms Available: 40/60 or 80/20 ratios
Application: Syringe format
Sterility: Sterile, single-use
Manufacturer: Septodont Inc.
Resorption Time:
40/60: 3–9 months
80/20: 9–12 months
Customer Ratings Average Rating: 4.9 out of 5 (based on clinician feedback)
Customer Feedback
Easy to handle and apply with syringe delivery
Excellent bone regeneration and scaffold support
Customizable resorption timeline fits various clinical needs
Reliable choice for advanced grafting procedures
