Comparison Table for Teeth Desensitizers
Product Name | Manufacturer | Size/Volume | Indications | Features |
---|---|---|---|---|
Micro Prime™ Desensitizer | Danville Materials | 10 ml Bottle | – Eliminates post-op sensitivity and discomfort from cervical erosions<br>- Can be used for desensitization of amalgam restorations | – Helps kill bacteria<br>- Alters nerve responses<br>- Aids bonding primers in penetrating etched dentin<br>- Compatible with all total-etch bonding systems, cements, and amalgam<br>- HEMA formulation reliably plugs tubules |
Gluma® Desensitizer – Bottle Refill | Heraeus Kulzer | 5 ml | – Treating cervical hypersensitivity and eliminating dentinal hypersensitivity<br>- Pretreatment to priming and bonding for direct composite restorations<br>- Prior to placing compomer and amalgam restorations | – No mixing or curing required<br>- Can be used with all bonding and restorative materials in any situation |
Patterson® Desensitizer | Patterson Dental | 10 ml | – Reducing post-op sensitivity under many restorative materials<br>- Ideal for abrasion, cervical erosions, and preps | – Contains HEMA to aid bonding primers penetrating etched dentin |
Telio CS Desensitizer | Ivoclar Vivadent | N/A | – Reducing or preventing dentinal hypersensitivity<br>- Temporary restorations<br>- Cementation of indirect restorations<br>- Direct restorative treatment<br>- Treatment of sensitive tooth necks | – Total working time of 10 seconds<br>- No light curing required<br>- Cleaning of cut dentin surfaces |
HurriSeal® Dentin Desensitizer | Parker Dental | 12 ml Bottle | – Wetting agent in bonding restorations<br>- Treating or preventing dentinal hypersensitivity associated with various conditions<br>- Permanent and temporary restorations | – Apply after etching and before priming/bonding<br>- Provides protection in 1-3 coats depending on patients’ needs<br>- Application lasts 6-9 months for cervical, or lifetime of restoration<br>- Soft tissue friendly (no glutaraldehyde)<br>- Universally compatible<br>- Simple to use with no mixing or light curing necessary |
Hemaseal & CIDE Desensitizer | Parkell | 10 ml Bottle | – Eliminating post-op sensitivity<br>- Compatible with all dentin adhesives | – Reduction of microleakage<br>- Soft-tissue friendly<br>- Increases bond strength up to 33% |
Riva Star Tooth Desensitizer | SDI | N/A | – Treatment of dentinal hypersensitivity<br>- For use in adults over 21 | – Contains both Step 1 silver diamine fluoride and Step 2 potassium iodide<br>- Forms immediate silver iodide precipitate with no staining on sound dentin and enamel |
Calm-it™ Desensitizer Bottle Refill | Premier Dental | 6 ml | – Prevention of dentinal hypersensitivity<br>- Compatible with adhesives, cements, restoratives, amalgams, core buildup, and temporary materials | – Reduces/eliminates sensitivity in seconds<br>- Penetrates deeply into tubules<br>- One-step chairside procedure |
Cervitec® Plus Chlorhexidine Varnish | Ivoclar Vivadent | N/A | – Protection of exposed root surfaces Treatment of open dentin tubules | – Contains chlorhexidine for antibacterial properties<br>- Varnish formulation for easy application |
Super Seal® – Phoenix Dental Inc | Phoenix Dental Inc | – Unique formula that removes the smear layer, seals the tubules and desensitizes in one step. |
Top 10 Mouthwashes & Rinses for Your Mouth and Teeth
1. Micro Prime™ Desensitizer, 10 ml Bottle – Danville Materials

Product Description
MicroPrime is applied to dentin to help reduce hypersensitivity by plugging tubules and modifying nerve response. It supports bacterial control and enhances the penetration of bonding primers into etched dentin. Available in MicroPrime B (original) and MicroPrime G, which is equivalent to Gluma.
Product Overview
Ideal for use under composites, crowns, amalgam, or cemented restorations, MicroPrime is compatible with all total-etch bonding systems and restorative materials. It offers a reliable, fast-acting solution to postoperative discomfort and sensitivity.
Key Features
- HEMA-based desensitizing agent
- Effectively plugs dentinal tubules
- Reduces post-op sensitivity and nerve response
- Aids in bonding primer penetration
- Compatible with all total-etch systems, cements, and amalgam
- MicroPrime G version equivalent to Gluma
Common Applications
- Cervical erosion desensitization
- Use under temporary, provisional, and final restorations
- Amalgam restoration desensitization (conventional or bonded)
- Enhancing dentin bonding in restorative procedures
Technical Specifications
Product Type: Desensitizing Agent
Formulation: HEMA-based
Bottle Size: 10 ml
Versions: MicroPrime B (original), MicroPrime G (Gluma-equivalent)
Compatibility: All total-etch bonding systems, cements, and amalgam
Manufacturer: Danville Materials
Brand: Micro Prime™
Customer Ratings
4.8 out of 5 stars
Customer Feedback
Great at eliminating post-op sensitivity
Works well under all types of restorations
A reliable alternative to Gluma
2. Gluma® Desensitizer – Bottle Refill, 5 ml

Product Description
Formulated for direct application, Gluma Desensitizer requires no mixing or curing. It penetrates exposed dentin tubules to eliminate hypersensitivity and can be used with all restorative materials, including compomers, amalgam, and direct composite restorations.
Product Overview
Gluma provides long-lasting desensitization and supports improved patient comfort. Its universal compatibility makes it suitable for use in virtually any restorative setting without interfering with bonding protocols.
Key Features
- Treats cervical and dentinal hypersensitivity
- No mixing or curing required
- Use before priming and bonding
- Compatible with composites, compomers, amalgam, and adhesives
- Convenient 5 ml refill bottle
Common Applications
- Desensitization of exposed dentin
- Pretreatment for direct composite bonding
- Before placement of compomer or amalgam restorations
- Managing cervical hypersensitivity
Technical Specifications
Product Type: Desensitizing Agent
Form: Liquid (ready to use)
Bottle Size: 5 ml
Application: No mixing or curing
Compatibility: All bonding agents and restorative materials
Manufacturer: Kulzer
Brand: Gluma®
Customer Ratings
4.9 out of 5 stars
Customer Feedback
Fast-acting and easy to apply
Highly effective for sensitive patients
Great compatibility with all restorations
3. Patterson® Desensitizer, 10 ml

Product Description
Formulated with HEMA, Patterson Desensitizer helps seal dentinal tubules while aiding the penetration of bonding primers into etched dentin. It is suitable for use in cases of cervical erosion, abrasion, and restorative preparations, and is compatible with most dentin resin bonding systems.
Product Overview
This desensitizer improves patient outcomes by minimizing hypersensitivity while supporting strong adhesion. Its versatility and ease of use make it a dependable addition to restorative workflows.
Key Features
- HEMA-based formulation
- Reduces post-op sensitivity
- Enhances bonding primer penetration
- Effective for abrasion, cervical erosions, and restorative preps
- Compatible with most dentin bonding materials
Common Applications
- Under composite and provisional restorations
- Cervical erosion and abrasion cases
- Pre-bonding application to etched dentin
- General restorative sensitivity control
Technical Specifications
Product Type: Desensitizing Agent
Formulation: HEMA-based
Bottle Size: 10 ml
Application: No mixing required
Compatibility: Most dentin resin bonding materials
Manufacturer: Patterson Dental Supply
Brand: Patterson®
Customer Ratings
4.7 out of 5 stars
Customer Feedback
Simple to use and very effective
Reduces sensitivity and improves bonding
Works well with a variety of restorative materials
4. Telio CS Desensitizer – Ivoclar

Product Description
Telio CS Desensitizer is applied directly to cut dentin surfaces to reduce sensitivity before temporary or permanent restorations. With a total working time of just 10 seconds and no light curing required, it is an efficient solution for chairside use across multiple clinical applications.
Product Overview
This versatile desensitizer is ideal for use during temporary restorations, cementation of indirect restorations, direct restorative treatments, and managing sensitive tooth necks. It provides dependable relief while maintaining procedural efficiency.
Key Features
- Clear desensitizing solution
- No light curing required
- Total working time: 10 seconds
- Effective on cut dentin surfaces
- Ideal for temporary and permanent restorative use
Common Applications
- Under temporary restorations
- Before cementation of indirect restorations
- During direct restorative treatment
- Treatment of sensitive cervical tooth areas
Technical Specifications
Product Type: Desensitizing Agent
Form: Liquid solution
Color: Clear
Working Time: 10 seconds
Curing Requirement: None
Application: Apply to cut dentin
Manufacturer: Ivoclar
Brand: Telio® CS
Customer Ratings
4.8 out of 5 stars
Customer Feedback
Fast and easy application—no curing is a plus
Great for both temp and final restoration sensitivity
Excellent results on sensitive cervical margins
5. HurriSeal® Dentin Desensitizer, 12 ml Bottle

Product Description
HurriSeal acts as a wetting agent in bonding restorations, helping to eliminate technique-sensitive steps. It is ideal for managing sensitivity from cervical erosion, exposed root surfaces, whitening procedures, scaling and root planing, and restorative treatments. Apply after etching and before bonding for optimal results.
Product Overview
This desensitizer provides effective protection with 1–3 coats depending on patient needs. One application lasts 6–9 months on cervical areas or for the full life of the restoration. Safe for soft tissue, HurriSeal enhances patient comfort without complicating clinical workflows.
Key Features
- Glutaraldehyde-free and soft tissue friendly
- Use after etching and before priming/bonding
- Long-lasting protection: 6–9 months or lifetime of restoration
- No mixing or light curing required
- Universally compatible with bonding materials
- Effective in 1–3 coats
Common Applications
- Cervical erosion and toothbrush abrasion
- Exposed root surface sensitivity
- Post-whitening sensitivity
- After periodontal scaling and root planing (post-healing)
- Under permanent and temporary restorations
Technical Specifications
Product Type: Dentin Desensitizer
Form: Liquid solution
Bottle Size: 12 ml
Application Timing: After etching, before bonding
Coating: 1–3 coats depending on severity
Curing: No light curing required
Compatibility: Universal with adhesives and restoratives
Manufacturer: Beutlich Pharmaceuticals
Brand: HurriSeal®
Customer Ratings
4.9 out of 5 stars
Customer Feedback
Long-lasting relief and easy to apply
No burn or irritation—great for soft tissues
Perfect for post-scaling sensitivity and restorative prep
6. Hemaseal & CIDE Desensitizer, 10 ml Bottle

Product Description
Hemaseal & CIDE is compatible with all dentin adhesives and helps increase bond strength by up to 33%. Its 4% chlorhexidine content not only blocks dentinal tubules but also inhibits microbial activity, making it ideal for a wide range of restorative procedures.
Product Overview
This soft-tissue friendly desensitizer reduces the risk of microleakage while improving the durability of restorations. It is easy to apply and integrates seamlessly into bonding protocols, making it a valuable addition to any adhesive system.
Key Features
- 4% chlorhexidine formula
- Eliminates post-op sensitivity
- Increases bond strength by up to 33%
- Reduces microleakage
- Compatible with all dentin adhesives
- Soft-tissue friendly
Common Applications
- Under direct and indirect restorations
- Post-operative sensitivity prevention
- Enhancing dentin bond durability
- Reducing microleakage in adhesive procedures
Technical Specifications
Product Type: Desensitizing Agent
Active Ingredient: 4% Chlorhexidine
Bottle Size: 10 ml
Compatibility: Universal with all dentin adhesives
Tissue Safety: Soft-tissue friendly
Manufacturer: ADVANCED DENTAL TECHNOLOGIES (specify if different)
Brand: Hemaseal & CIDE
Customer Ratings
4.8 out of 5 stars
Customer Feedback
Great desensitizer and antimicrobial in one
Boosts bond strength noticeably
Easy to use—excellent for all adhesive procedures
7. Riva Star Tooth Desensitizer

Product Description
Riva Star is designed to immediately block exposed dentinal tubules and reduce hypersensitivity. The dual-step process minimizes the common discoloration associated with silver diamine fluoride, making it ideal for patients concerned about esthetics. Recommended for adult patients over the age of 21.
Product Overview
By forming silver iodide in situ, Riva Star offers rapid, visible results without compromising appearance. It is applied chairside in just minutes and is an excellent choice for long-term sensitivity relief in adult patients.
Key Features
- Two-step desensitizing system (SDF + KI)
- Creates immediate silver iodide precipitate
- No staining of sound enamel or dentin
- Effectively treats dentinal hypersensitivity
- Easy and quick in-office application
- For use in adults aged 21 and over
Common Applications
- Treatment of dentinal hypersensitivity
- Desensitization before or after restorative procedures
- Sensitivity control for exposed root surfaces
Technical Specifications
Product Type: Two-Step Desensitizing Agent
Active Ingredients: Silver Diamine Fluoride (Step 1), Potassium Iodide (Step 2)
Staining: None on sound enamel/dentin
Indication: Dentinal hypersensitivity in adults
Age Restriction: For patients 21+
Manufacturer: SDI Limited
Brand: Riva Star
Customer Ratings
4.8 out of 5 stars
Customer Feedback
Instant sensitivity relief without staining
Patients love the fast results
Great for esthetic zones—no discoloration
8. Calm-it™ Desensitizer Bottle Refill, 6 ml

Product Description
Calm-it penetrates deep into dentinal tubules to reduce or eliminate sensitivity within seconds. Its fast-acting formula is compatible with adhesives, cements, composites, amalgams, core buildup materials, and temporaries—making it a versatile choice for a variety of procedures.
Product Overview
Designed for simplicity and speed, Calm-it can be applied in a single step during routine chairside treatment. It provides lasting relief and promotes better patient comfort with minimal chair time.
Key Features
- Fast, one-step application
- Penetrates deeply into dentinal tubules
- Eliminates sensitivity in seconds
- Compatible with all restorative and bonding materials
- Easy chairside integration
Common Applications
- Desensitization under direct and indirect restorations
- Sensitivity relief during crown and bridge procedures
- Use with core buildup, temporary restorations, or amalgam
- Chairside sensitivity control for exposed dentin
Technical Specifications
Product Type: Desensitizing Agent
Form: Liquid
Bottle Size: 6 ml
Application: One-step, chairside use
Compatibility: Adhesives, cements, restoratives, amalgam, temporaries
Manufacturer: (Specify if known)
Brand: Calm-it™
Customer Ratings
4.7 out of 5 stars
Customer Feedback
Instant relief—works in seconds
Super easy to use with any material
Great for patients with high sensitivity
9. Cervitec® Plus Chlorhexidine Varnish – Ivoclar

Product Description
This transparent, colorless varnish provides targeted, selective application for protecting exposed cervical margins, crown and bridge work, proximal areas, fissures, and grooves. Its homogenous formulation ensures even coverage and sustained effectiveness without compromising appearance—making it ideal for anterior applications.
Product Overview
Cervitec Plus enhances the quality and durability of restorative work by protecting vulnerable tooth surfaces against microbial exposure and hypersensitivity. Its esthetic clarity and antimicrobial strength make it an excellent choice for high-visibility areas and long-term preventive care.
Key Features
- 1% chlorhexidine and 1% thymol formula
- Long-lasting antimicrobial protection
- Transparent, colorless varnish for esthetic zones
- Ideal for anterior teeth and visible areas
- Easy, selective application
- Supports protection of restorative margins and open tubules
Common Applications
- Protection of exposed root surfaces
- Treatment of open dentin tubules
- Around crowns and bridges
- In fissures, grooves, and proximal areas
- Esthetic dental zones requiring clear material
Technical Specifications
Product Type: Desensitizing/Protective Varnish
Form: Homogenous liquid varnish
Active Ingredients: 1% Chlorhexidine, 1% Thymol
Color: Clear, transparent
Application: Selective varnish for targeted areas
Manufacturer: Ivoclar
Brand: Cervitec® Plus
Customer Ratings
4.9 out of 5 stars
Customer Feedback
Perfect for anterior teeth—no visible coating
Effective protection and easy to apply
A go-to product for open tubules and crown margins
10. Super Seal® – Phoenix Dental Inc

Product Description
Super Seal requires no pumice cleaning or rinsing. Upon application, its acidic nature demineralizes the smear layer and peritubular dentin, reacting with calcium hydroxyapatite to form a calcium oxalate precipitate. This reaction seals and protects exposed dentin, enamel, and cementum with an acid-resistant barrier that integrates with the tooth surface.
Product Overview
Ideal for pre-restorative desensitization, Super Seal is fast-acting, effective, and efficient. Its ability to chemically bind with dentin substrates provides both immediate and durable desensitizing effects.
Key Features
- Removes smear layer and desensitizes in one step
- No rinsing or pumice cleaning required
- Forms calcium oxalate precipitate within seconds
- Acid-resistant liner chemically bonds to dentin
- Seals dentinal tubules to reduce hypersensitivity
- Compatible with enamel, dentin, and cementum surfaces
Common Applications
- Pre-restorative desensitization
- Treatment of exposed dentin and cementum
- Smear layer removal and tubule sealing
- Sensitivity control on vital teeth
Technical Specifications
Product Type: One-Step Desensitizer and Tubule Sealant
Mechanism: Calcium oxalate formation
Application Steps: No rinsing or pre-cleaning required
Substrate Compatibility: Dentin, enamel, cementum
Manufacturer: Phoenix Dental Inc
Brand: Super Seal®
Customer Ratings
4.8 out of 5 stars
Customer Feedback
Highly effective—instant desensitization
No need to rinse or scrub—very convenient
A must-have for smear layer removal and tubule sealing