Comparison Table for Dental Adhesives Dental Adhesive Refill Type Compatible Techniques Indications Key Features Scotchbond™ Universal Adhesive Vial/Refill Total-Etch, Self-Etch, Selective-Etch Direct and indirect applications on enamel, dentin, glass ceramic, zirconia, alloys, and composites Consistent bond strength to both moist and dry etched dentin, virtually no post-op sensitivity, excellent marginal integrity, 1 step, 1 coat adhesive application, self- and dual-cure compatible, no refrigeration needed Prime & Bond elect™ Bottle/Unit Doses Total-Etch Direct restorations, root surface desensitization, veneers Minimizes exposure to etchant, high bond strength, minimal microleakage, reinforced hybrid and adhesive layers, protection against sensitivity, consistent bond strength with varied moisture levels, lower film thickness of resin-dentin and resin-enamel interfaces OptiBond™ Solo Plus Bottle Refill Self-Etch, Total-Etch Direct and indirect bonding of composites, amalgam, porcelain, inlays, onlays, veneers, crowns, and posts Fluoride release, ethanol-based, added indications OptiBond™ Solo Plus Unidose™ Refill Unit Doses Self-Etch, Total-Etch Direct and indirect bonding of composites, amalgam, porcelain, inlays, onlays, veneers, crowns, and posts Fluoride release, ethanol-based, added indications Prime & Bond elect™ – DENTSPLY Caulk Unit Doses Total-Etch Direct restorations, root surface desensitization, veneers Minimizes exposure to etchant, high bond strength, minimal microleakage, reinforced hybrid and adhesive layers, protection against sensitivity, consistent bond strength with varied moisture levels, lower film thickness of resin-dentin and resin-enamel interfaces Scotchbond™ Universal Adhesive Unit Dose Kits Unit Doses Total-Etch, Self-Etch, Selective-Etch Direct and indirect applications on enamel, dentin, glass ceramic, zirconia, alloys, and composites Consistent bond strength to both moist and dry etched dentin, virtually no post-op sensitivity, excellent marginal integrity, 1 step, 1 coat adhesive application, self- and dual-cure compatible, no refrigeration needed G-Premio™ BOND Refill Total-Etch, Self-Etch, Selective-Etch Direct restorations, repairs of glass or hybrid ceramics Compatible with all dental materials, ideal for hypersensitivity, light-cured, low film thickness Adper™ Single Bond Plus™ Adhesive Refill Total-Etch Direct restorations, indirect restorations, root surface desensitization, veneers Excellent bonding to dentin and enamel, stable nanofiller, convenient bottle design, reduces risk of post-operative sensitivity iBOND® Universal Bottle Refill Total-Etch, Self-Etch, Selective-Etch Direct and indirect applications on all dental materials Excellent dentin penetration and instant reliable bond strength, easier air-drying, reduced technique sensitivity, no dual-cure activator needed Bond-1® Single Step Bonding System Primer/Adhesive Total-Etch Direct and indirect bonding of composites, porcelains, metal restorations, and amalgam to tooth structure Helps
Top 10 Bonding Agents & Adhesives Miscellaneous
1. Scotchbond™ Universal Adhesive Vial

Product Description
Scotchbond Universal Adhesive is a single-component bonding agent designed for use in all etching techniques—total-etch, self-etch, and selective-etch. It supports both direct and indirect restorative procedures and provides reliable adhesion to a wide range of dental materials without the need for separate primers.
Product Overview
Manufactured by 3M, Scotchbond Universal offers consistent bond strength to both moist and dry dentin, along with excellent marginal integrity. Its one-step, one-coat application saves time and reduces technique sensitivity. The formula is compatible with self- and dual-cure systems and does not require refrigeration, with a 2-year shelf life at room temperature.
Key Features
- One-step, one-coat adhesive for fast application
- Compatible with total-etch, self-etch, and selective-etch techniques
- Bonds to enamel, dentin, glass ceramics, zirconia, composites, and alloys
- No separate primer needed for bonding to multiple substrates
- Consistent bond strength to both moist and dry dentin
- Excellent marginal seal for esthetic restorations
- Virtually no postoperative sensitivity
- Self- and dual-cure compatible
- 2-year shelf life at room temperature
Common Applications
- Bonding of direct composite restorations
- Cementation of indirect restorations
- Repair of composite, ceramic, and metal restorations
- Use with self- or dual-cure core build-up materials
Technical Specifications
- Product Type: Universal Adhesive
- Curing: Light-cure; compatible with self- and dual-cure systems
- Application: 1-step, 1-coat
- Etching Compatibility: Total-etch, self-etch, selective-etch
- Storage: Room temperature (no refrigeration required)
- Shelf Life: 2 years
- Manufacturer: 3M
Customer Ratings
4.9 out of 5 stars (based on bond strength and clinical efficiency)
Customer Feedback
Quick and dependable with excellent bond strength
Truly universal—works on all materials
No sensitivity and great marginal seal
Top 10 Dual-Cure Dental Bonding Agents
2. Prime & Bond elect™

Product Description
Prime & Bond elect is a single-component, light-cured universal adhesive that offers strong adhesion to enamel and dentin while minimizing postoperative sensitivity. Its acetone-based chemistry displaces moisture, allowing deep resin and filler penetration into dentinal tubules and forming a durable hybrid layer.
Product Overview
Manufactured by Dentsply Sirona, Prime & Bond elect delivers consistent bond strength across various moisture conditions. It helps reduce microleakage, promotes a tight marginal seal, and features a low film thickness that preserves the integrity of resin-dentin and resin-enamel interfaces—making it ideal for both esthetic and structural restorations.
Key Features
- Acetone-based formulation enhances resin penetration and displaces water
- Minimizes postoperative sensitivity by sealing dentin effectively
- Provides consistent bond strength regardless of dentin moisture levels
- Low film thickness maintains precision in marginal adaptation
- Reinforces both hybrid and adhesive layers for long-lasting durability
- Helps reduce microleakage for better marginal seal
Common Applications
- Bonding of direct composite restorations
- Indirect restorations including veneers, inlays, and onlays
- Core build-ups
- Compatible with self-, dual-, and light-cure resin systems
Technical Specifications
- Product Type: Universal Adhesive
- Curing: Light-cure
- Etching Compatibility: Self-etch, total-etch, selective-etch (when used with phosphoric acid)
- Solvent: Acetone
- Film Thickness: Low
- Manufacturer: Dentsply Sirona
Customer Ratings
4.8 out of 5 stars (based on sensitivity control and clinical reliability)
Customer Feedback
Strong, reliable bond every time
Virtually no sensitivity issues
Works well even on slightly moist dentin
3. OptiBond™ Solo Plus

Product Description
OptiBond Solo Plus is a single-component, light-cure adhesive designed for both direct and indirect restorations. With a 0.4-micron filler for enhanced mechanical properties and fluoride release, it offers strong, reliable bonds across a wide range of materials and indications.
Product Overview
Manufactured by Kerr Restoratives, OptiBond Solo Plus uses ethanol as its solvent instead of acetone, allowing for better handling in moist environments. It provides strong adhesion to composite, amalgam, porcelain, and tooth structure, making it a versatile option for both routine and advanced restorative procedures.
Key Features
- One-bottle adhesive for both direct and indirect bonding
- Ethanol-based formulation for greater technique tolerance
- Filled with 0.4-micron particles for increased bond strength
- Fluoride-releasing for added protection and remineralization
- Bonds to composite, amalgam, porcelain, dentin, and enamel
- Supports inlays, onlays, crowns, veneers, and post cementation
Common Applications
- Bonding direct composite restorations
- Indirect bonding of inlays, onlays, crowns, veneers, and posts
- Adhesion to a variety of restorative materials including metal and porcelain
- Fluoride-releasing protection in high-caries-risk patients
Technical Specifications
- Product Type: Total-Etch Adhesive
- Curing: Light-cure
- Solvent: Ethanol
- Filler: 0.4-micron particles
- Fluoride Release: Yes
- Etching Requirement: Requires phosphoric acid etching
- Manufacturer: Kerr Restoratives
Customer Ratings
4.8 out of 5 stars (based on versatility and bond performance)
Customer Feedback
Great for both direct and indirect cases
Fluoride release is a bonus for patient care
Ethanol base makes it easy to control in moist conditions
4. OptiBond™ Solo Plus Unidose™

Product Description
OptiBond Solo Plus Unidose is a single-component, light-cure adhesive designed for both direct and indirect bonding procedures. Offered in convenient single-use packaging, it delivers consistent performance with the added benefits of fluoride release and ethanol-based formulation for improved clinical handling.
Product Overview
Manufactured by Kerr Restoratives, this adhesive contains 0.4-micron fillers to enhance bond strength and mechanical integrity. It bonds effectively to enamel, dentin, composite, amalgam, and porcelain, making it a versatile choice for a wide range of restorative indications. The Unidose format improves hygiene, eliminates waste, and simplifies chairside workflow.
Key Features
- Single-dose packaging for improved efficiency and infection control
- Ethanol-based formula allows better moisture control compared to acetone
- 0.4-micron filler enhances strength and durability
- Fluoride-releasing for added clinical protection
- Bonds to composite, amalgam, porcelain, and tooth structures
- Suitable for both direct and indirect restorations
Common Applications
- Bonding direct composite restorations
- Indirect bonding of crowns, inlays, onlays, veneers, and posts
- Use with amalgam and porcelain restorations
- Fluoride-releasing protection for caries-prone patients
Technical Specifications
- Product Type: Total-Etch Adhesive
- Delivery Form: Unidose
- Curing: Light-cure
- Solvent: Ethanol
- Filler: 0.4-micron particles
- Fluoride Release: Yes
- Manufacturer: Kerr Restoratives
Customer Ratings
4.8 out of 5 stars (based on convenience and clinical effectiveness)
Customer Feedback
Love the single-dose—no mess and minimal waste
Strong, reliable bond with fluoride protection
Easy to use in both direct and indirect cases
5. Prime & Bond elect™ – Unit Doses – DENTSPLY Caulk

Product Description
Prime & Bond elect in Unit Dose packaging is a single-component, light-cure adhesive that offers strong, dependable bonding to both enamel and dentin. Its acetone-based chemistry promotes optimal penetration into dentinal tubules, displacing moisture for a reinforced bond and excellent sealing.
Product Overview
Manufactured by Dentsply Caulk, this adhesive minimizes postoperative sensitivity while providing consistent bond strength across a range of moisture conditions. The unit dose format ensures hygienic, efficient, single-use delivery for every patient, while maintaining the same clinical effectiveness as the bottle version.
Key Features
- Unit dose packaging for convenience and infection control
- Acetone-based formula promotes deep resin infiltration
- Reinforces hybrid and adhesive layers
- Virtually eliminates postoperative sensitivity
- Minimizes microleakage to maintain marginal seal integrity
- Consistent bond strength on both moist and dry dentin
- Thin film layer for precise marginal fit
Common Applications
- Bonding of direct composite restorations
- Cementation of indirect restorations
- Core build-ups and desensitization
- Ideal for moisture-variable clinical environments
Technical Specifications
- Product Type: Universal Adhesive
- Delivery Form: Unit Dose
- Curing: Light-cure
- Solvent: Acetone
- Etching Compatibility: Self-etch, total-etch, selective-etch
- Film Thickness: Low
- Manufacturer: Dentsply Caulk
Customer Ratings
4.9 out of 5 stars (based on sensitivity control and ease of application)
Customer Feedback
Unit doses are perfect for efficiency and hygiene
Excellent bond with no post-op sensitivity
Reliable in both dry and moist dentin cases
6. Scotchbond™ Universal Adhesive Unit Dose Kits – 3M

Product Description
Scotchbond Universal Adhesive Unit Dose Kits offer a convenient, hygienic solution for universal bonding. This single-component adhesive supports all etching techniques—total-etch, self-etch, and selective-etch—and is suitable for both direct and indirect restorative procedures. It bonds to a wide range of dental materials without the need for additional primers.
Product Overview
Manufactured by 3M, Scotchbond Universal delivers strong, reliable bonds to enamel, dentin, glass ceramics, zirconia, metals, and composites. The unit dose format simplifies chairside use, minimizes cross-contamination, and ensures consistent application. It maintains excellent bond strength on both moist and dry dentin and eliminates the need for refrigeration.
Key Features
- One-step, one-coat adhesive application
- Compatible with all etching techniques: total-etch, self-etch, and selective-etch
- Bonds to enamel, dentin, zirconia, glass ceramic, metals, and composites
- Delivers consistent bond strength to moist or dry etched dentin
- Virtually eliminates postoperative sensitivity
- Excellent marginal integrity for esthetic restorations
- Self- and dual-cure compatible
- Room temperature storage with a 2-year shelf life
- Unit dose format for easy, hygienic single-use application
Common Applications
- Direct composite restorations
- Adhesive cementation of indirect restorations
- Repairs of ceramic, composite, and metal restorations
- Core build-ups and bonding in variable moisture conditions
Technical Specifications
- Product Type: Universal Adhesive
- Delivery Form: Unit Dose Kit
- Curing: Light-cure; compatible with self- and dual-cure systems
- Etching Compatibility: Total-etch, self-etch, selective-etch
- Storage: Room temperature
- Shelf Life: 2 years
- Manufacturer: 3M
Customer Ratings
4.9 out of 5 stars (based on ease of use, bond strength, and cleanliness)
Customer Feedback
Unit doses are efficient and clean
Bonds beautifully to every surface with no sensitivity
Perfect for fast-paced or multi-op practices
7. G-Premio™ BOND – Refill – GC America Inc

Product Description
G-Premio BOND is a light-cured universal bonding agent designed for direct restorations and repair of indirect restorations. It provides strong, reliable adhesion with minimal film thickness and can be used with all etching protocols—total-etch, self-etch, and selective-etch.
Product Overview
Manufactured by GC America Inc, G-Premio BOND offers excellent bond strength and versatility across multiple clinical applications. It is ideal for use in hypersensitive cases and requires no additional primer when repairing glass or hybrid ceramics. With a film thickness of just 3 microns, it ensures a precise fit and smooth adaptation of restorations.
Key Features
- Universal adhesive compatible with total-, self-, and selective-etch techniques
- Light-cured with a low film thickness of 3 microns
- Can be used without primer for repairs of glass and hybrid ceramic restorations
- Ideal for use in cases with hypersensitivity
- Suitable for all direct restorations and selective repair of indirect restorations
- Provides strong adhesion to enamel and dentin
Common Applications
- Direct composite restorations
- Repair of fractured glass or hybrid ceramic restorations
- Bonding in hypersensitive dentin cases
- Adhesive cementation with light-cured composites
Technical Specifications
- Product Type: Universal Bonding Agent
- Curing: Light-cure
- Etching Compatibility: Total-etch, self-etch, selective-etch
- Film Thickness: 3 microns
- Primer Requirement: Not needed for ceramic/hybrid ceramic repair
- Manufacturer: GC America Inc
Customer Ratings
4.8 out of 5 stars (based on versatility and sensitivity control)
Customer Feedback
Excellent bond and incredibly thin film
No primer needed saves time in repairs
Perfect for sensitive teeth cases and routine restorations
8. Adper™ Single Bond Plus™ Adhesive Refill, 6 g

Product Description
Adper Single Bond Plus is a total-etch, light-cure adhesive designed for reliable bonding in a variety of clinical applications. It features 3M’s moisture-tolerant Vitrebond copolymer, which enhances adhesion to moist dentin and enamel while minimizing postoperative sensitivity.
Product Overview
This ethanol-based adhesive maintains stability and resists evaporation during placement. It is indicated for use in both direct and indirect restorations, as well as for root surface desensitization and veneer bonding. The nanofiller in the formula remains evenly suspended—no shaking required—ensuring consistent performance from the first drop to the last.
Key Features
- Total-etch technique with strong bond to dentin and enamel
- Ethanol/water solvent resists evaporation on the tooth
- Contains Vitrebond copolymer for enhanced moisture tolerance
- Stable nanofiller dispersion—no shaking needed
- Convenient bottle design for clean dispensing
- Reduces risk of postoperative sensitivity
Common Applications
- Bonding of direct composite restorations
- Cementation of indirect restorations (after light curing)
- Veneer bonding
- Root surface desensitization
Technical Specifications
- Product Type: Total-Etch Adhesive
- Curing: Light-cure
- Solvent: Ethanol/water
- Nanofiller: Yes (does not settle)
- Etching Technique: Requires phosphoric acid etching
- Volume: 6 g bottle
- Manufacturer: 3M
Customer Ratings
4.8 out of 5 stars (based on clinical performance and ease of use)
Customer Feedback
Reliable and consistent every time
Great moisture control with no sensitivity
Love that it doesn’t need shaking—super convenient
9. iBOND® Universal – Kulzer

Product Description
iBOND Universal is a light-cure, single-component adhesive designed for all bonding techniques and dental materials. Whether using self-etch, selective-etch, or total-etch methods, this universal adhesive provides dependable bond strength with reduced technique sensitivity.
Product Overview
Manufactured by Kulzer, iBOND Universal features advanced dentin penetration for immediate and reliable bonding performance. The formulation allows for easier air-drying and does not require a separate dual-cure activator, making it simple and efficient to use across a wide range of clinical indications.
Key Features
- Universal adhesive for self-etch, selective-etch, and total-etch techniques
- Compatible with all direct and indirect materials
- No dual-cure activator required
- Excellent penetration into dentin for strong, long-lasting bonds
- Simple air-drying with minimized technique sensitivity
- Light-cure formula with broad application versatility
Common Applications
- Direct composite restorations
- Adhesive cementation of indirect restorations
- Core build-ups and post cementation
- Desensitization of exposed dentin
Technical Specifications
- Product Type: Universal Adhesive
- Curing: Light-cure
- Etching Compatibility: Self-etch, selective-etch, total-etch
- Activator Requirement: None (dual-cure compatible without activator)
- Delivery Form: Bottle refill
- Manufacturer: Kulzer
Customer Ratings
4.8 out of 5 stars (based on ease of use and reliable performance)
Customer Feedback
Great all-in-one adhesive—works with any technique
Strong bond and no sensitivity
Very forgiving and easy to apply, even for less experienced users
10. Bond-1® Single Step Bonding System – Primer/Adhesive – Pentron

Product Description
Bond-1 Single Step Bonding System is a 5th generation, total-etch adhesive that combines primer and adhesive in a single bottle. It provides strong, reliable bonds to both dentin and enamel while helping to minimize postoperative sensitivity.
Product Overview
Manufactured by Pentron, Bond-1 is an extremely versatile adhesive system suitable for both direct and indirect restorations. It is compatible with light-, self-, and dual-cure materials, and can be used with composites, porcelains, metal restorations, and amalgam. Its low film thickness ensures optimal adaptation and bonding surface.
Key Features
- One-bottle total-etch system (primer + adhesive)
- High bond strength to enamel and dentin
- Compatible with light-, self-, and dual-cure composites
- Bonds to a wide range of restorative materials including porcelain, metal, and amalgam
- Helps reduce postoperative sensitivity
- Low film thickness preserves restoration fit and precision
Common Applications
- Direct composite restorations
- Indirect restorations including crowns, inlays, onlays, and veneers
- Bonding of metal, porcelain, and amalgam restorations
- Core build-ups and post cementation
Technical Specifications
- Product Type: Total-Etch Adhesive (5th generation)
- Curing: Light-cure; compatible with self- and dual-cure systems
- Bottle Type: Primer/Adhesive combined
- Etching Requirement: Phosphoric acid required
- Film Thickness: Low
- Manufacturer: Pentron
Customer Ratings
4.7 out of 5 stars (based on versatility and ease of use)
Customer Feedback
Great all-around adhesive—strong and dependable
No issues with sensitivity
Thin and easy to use, even with indirect restorations