Comparison Table for Endodontic Medicaments
Item | Brand | Description | Package Size | Main Use |
---|---|---|---|---|
1 | RC-Prep® | Chemo-Mechanical Preparation of Root Canals – Jar | Jar | Lubricates canals, removes calcifications |
2 | Sodium Hypochlorite 6% Solution | Vista Dental | 6% Solution, 16 oz Bottle | Irrigation, debridement, disinfection of root canals |
3 | Vitapex® Calcium Hydroxide Paste with Iodoform | Regular Kit, 2.0 g | Regular Kit, 2.0 g | Temporary or permanent root canal filling material |
4 | EDTA 17% Aqueous Solution | Vista Dental Products | 17% Aqueous Solution | Endodontic irrigation, removal of smear layer and dentin mud |
5 | Formo-Cresol | Cresol Master-Dent® | 1 oz Bottle | Treatment of putrescent or necrotic pulps |
6 | Patterson® EDTA Solution, 17% | Patterson Dental Supply | 17% EDTA Solution | Aid in root canal instrumentation |
7 | Endo-Cleanse – 17% EDTA Solution | Roydent Dental | 17% EDTA Solution, 1/Pkg | Softening and instrumentation of canal walls |
8 | Multi-Cal™ Calcium Hydroxide Preparation Kit | Multi-Cal™ | N/A | Temporary and intermediate root canal therapy, direct pulp capping, dentin bridge formation |
9 | Vista-Cal™ – Visco-Tips™ | Vista Dental Products | 50/Pkg | Improves flowability of viscous materials, delivers calcium hydroxide with precision |
10 | Glyde™ File Prep Root Canal Conditioner | Syringe Kit | Syringe Kit | Softens calcification, aids in cleansing root canal system |
1. RC-Prep® Chemo-Mechanical Preparation of Root Canals – Jar

Product Description
RC-Prep® is a chemo-mechanical root canal preparation material formulated with glycol, urea peroxide, and EDTA in a water-soluble base. It aids in the removal of calcifications and lubricates canals, promoting smoother, more efficient instrumentation during endodontic procedures.
Product Overview
Designed to reduce binding of reamers and files, RC-Prep enhances instrument movement and increases procedural safety. It is also ideal for use with apex locators, providing consistent and reliable readings throughout the procedure.
Key Features
- Glycol, urea peroxide, and EDTA formulation
- Water-soluble base for easy rinsing
- Lubricates canals and removes calcifications
- Facilitates smooth instrument movement
- Compatible with apex locators for accurate readings
- Reduces file binding and enhances efficiency
Common Applications
- Chemo-mechanical preparation of root canals
- Use with hand or rotary files during endodontic procedures
- Enhancing accuracy of apex locator readings
Technical Specifications
Product Name: RC-Prep®
Product Type: Root Canal Preparation Lubricant
Formulation: Glycol, Urea Peroxide, EDTA
Base: Water-Soluble
Application: Jar
Use With: Files, reamers, and apex locators
Manufacturer: Premier Dental
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Excellent lubrication and reliable apex locator performance
Makes root canal prep smoother and safer
Top 10 Endodontic Rotary Files
2. Sodium Hypochlorite 6% Solution – 16 oz Bottle

Product Description
Sodium Hypochlorite 6% Solution by Vista Dental is an aqueous disinfecting solution used for irrigation, debridement, and microbial control during root canal procedures. It supports thorough cleansing of the canal system before obturation.
Product Overview
With a 6% concentration, this endodontic irrigant effectively dissolves organic tissue and eliminates microorganisms from the canal space. The 16 oz bottle provides a cost-effective and convenient supply for routine use in endodontic treatments.
Key Features
- 6% sodium hypochlorite concentration
- Effective for canal irrigation and disinfection
- Dissolves organic tissue and aids in debridement
- Supports thorough cleansing during root canal therapy
- Supplied in a 16 oz bottle for clinical convenience
Common Applications
- Irrigation during endodontic procedures
- Debridement and disinfection of root canals
- Use during and after canal instrumentation
Technical Specifications
Product Name: Sodium Hypochlorite Solution – 6%
Product Type: Endodontic Irrigant
Concentration: 6%
Form: Aqueous Solution
Size: 16 oz Bottle
Package Quantity: 1/Pkg
Manufacturer: Vista Dental
Customer Ratings
Rating: 4.7 out of 5 (Based on verified reviews)
Customer Feedback
Reliable strength for consistent root canal disinfection
Good volume and value — essential for every endo setup
3. Vitapex® Calcium Hydroxide Paste with Iodoform

Product Description
Vitapex® is a premixed calcium hydroxide paste with iodoform, formulated for use as a temporary or permanent root canal filling material following pulpectomy. Its convenient syringe delivery system simplifies application and eliminates the need for mixing.
Product Overview
Designed for easy access to the apex, Vitapex® provides excellent antibacterial and bacteriostatic effects. It promotes apexification and apexogenesis, making it suitable for a wide range of endodontic treatments. The radiopaque formulation ensures visibility on radiographs for accurate placement verification.
Key Features
- Premixed calcium hydroxide with iodoform
- Used for temporary or permanent canal filling
- Antibacterial and bacteriostatic properties
- Promotes apexification and apexogenesis
- Radiopaque for precise placement tracking
- Delivered in syringe form for mess-free application
- Plunger-type system provides easy access to apex
Common Applications
- Root canal filling after pulpectomy
- Apexification and apexogenesis in immature teeth
- Use in pediatric endodontics and retreatment cases
Technical Specifications
Product Name: Vitapex® Calcium Hydroxide Paste with Iodoform
Product Type: Root Canal Filling Material
Formulation: Calcium Hydroxide + Iodoform
Delivery System: Pre-filled Syringe
Radiopacity: Yes
Antibacterial Properties: Yes
Manufacturer: Neo Dental
Customer Ratings
Rating: 4.9 out of 5 (Based on verified reviews)
Customer Feedback
Fast, easy application with excellent results
Highly effective in apexification cases — a staple in our endo practice
4. EDTA 17% Aqueous Solution – Vista Dental Products

Product Description
EDTA 17% Aqueous Solution by Vista Dental Products is an effective endodontic irrigant designed to remove the smear layer and dentin debris (dentin mud) from root canals. It enhances canal cleanliness and prepares the dentin surface for optimal adhesion of filling materials.
Product Overview
Formulated with an ideal pH for efficient chelation, this 17% EDTA solution opens dentinal tubules and improves the bonding environment within the root canal system. It is an essential step for enhancing the effectiveness of obturation and sealing.
Key Features
- 17% EDTA aqueous solution for endodontic irrigation
- Removes smear layer and dentin mud
- Opens dentinal tubules to improve bonding
- Optimized pH for enhanced chelating action
- Prepares canal walls for better adhesion of filling materials
Common Applications
- Final irrigation step in root canal therapy
- Smear layer removal
- Enhancing dentin surface for sealer and obturation adhesion
Technical Specifications
Product Name: EDTA 17% Aqueous Solution
Product Type: Endodontic Irrigant / Chelating Agent
Concentration: 17%
Form: Aqueous Solution
Function: Smear layer removal, dentin conditioning
Manufacturer: Vista Dental Products
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Effective smear layer removal every time
Great consistency and easy to use in irrigation protocol
5. Formo-Cresol – 1 oz Bottle

Product Description
Master-Dent® Formo-Cresol is a pulpal medicament primarily used in the treatment of putrescent or necrotic pulps. It offers bactericidal properties and is commonly used in pulpotomy and endodontic procedures.
Product Overview
Formo-Cresol is a proven agent for disinfecting the pulp chamber and root canal system. It is supplied in a 1 oz bottle and is typically applied with a cotton pellet during root canal therapy or pulpal treatment.
Key Features
- Used for treatment of necrotic or infected pulps
- Bactericidal and tissue-fixative properties
- Ideal for pulpotomy procedures
- Easy application with cotton pellet
- Supplied in 1 oz bottle for routine clinical use
Common Applications
- Pulpotomy in primary teeth
- Disinfection of root canals in non-vital teeth
- Temporary intracanal medicament
Technical Specifications
Product Name: Formo-Cresol
Product Type: Pulpal Medicament
Size: 1 oz
Form: Liquid Bottle
Application: Cotton pellet
Package Quantity: 1/Pkg
Manufacturer: Master-Dent®
Customer Ratings
Rating: 4.7 out of 5 (Based on verified reviews)
Customer Feedback
Effective and reliable for pulpotomies
Long-trusted material for non-vital pulp treatment
6. Patterson® EDTA Solution, 17% – Patterson Dental Supply

Product Description
Patterson® EDTA Solution is a 17% neutral pH aqueous solution used to aid in root canal instrumentation by effectively removing the smear layer and conditioning dentin for optimal obturation.
Product Overview
Ideal as a final rinse during endodontic procedures, this EDTA solution opens dentinal tubules, promotes better adhesion of sealers, and enhances canal cleanliness. It is available in both bottle and unit dose formats to suit practice preferences.
Key Features
- 17% EDTA for smear layer and debris removal
- Neutral pH for effective and gentle chelation
- Opens dentin tubules to improve adhesion
- Excellent final rinse before obturation
- Offered in bottle or unit dose packaging
Common Applications
- Final rinse in root canal therapy
- Removal of smear layer and dentin mud
- Preparation of canal walls for sealing and obturation
Technical Specifications
Product Name: Patterson® EDTA Solution
Product Type: Endodontic Irrigant / Chelating Agent
Concentration: 17%
pH Level: Neutral
Packaging Options: Bottle or Unit Dose
Use: Final Rinse in Root Canal Treatment
Manufacturer: Patterson Dental Supply
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Consistent performance and easy to use
Great for final rinse—cleans canals thoroughly and supports strong adhesion
7. Endo-Cleanse – 17% EDTA Solution – Roydent Dental

Product Description
Endo-Cleanse 17% EDTA Solution by Roydent Dental is a chelating agent formulated to aid in root canal irrigation and instrumentation. It effectively softens canal walls and removes the smear layer to improve bonding and sealing.
Product Overview
With a neutral pH and 17% EDTA concentration, Endo-Cleanse is ideal for use as a final rinse during endodontic therapy. It enhances canal cleanliness, opens dentinal tubules, and prepares surfaces for obturation.
Key Features
- 17% EDTA solution with neutral pH
- Softens and conditions canal walls
- Removes smear layer and dentin debris
- Ideal for final rinse during root canal procedures
- Improves adhesion and sealer penetration
Common Applications
- Final irrigation step in endodontic treatment
- Smear layer removal
- Preparation of canal walls for obturation
Technical Specifications
Product Name: Endo-Cleanse – 17% EDTA Solution
Product Type: Endodontic Irrigant / Chelating Agent
Concentration: 17%
pH Level: Neutral
Use: Irrigation during root canal therapy
Manufacturer: Roydent Dental
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Dependable EDTA rinse — leaves canals clean and ready for obturation
Great consistency and easy to work with
8. Multi-Cal™ Calcium Hydroxide Preparation Kit

Product Description
Multi-Cal™ is a creamy, ready-to-use calcium hydroxide preparation recommended for a wide range of clinical applications. With a pH greater than 12, it offers bactericidal and bacteriostatic properties, making it ideal for pulp therapy and root canal procedures.
Product Overview
This radiopaque formulation supports dentin bridge formation and is easy to apply for temporary or intermediate root canal therapy, pulp capping, and cavity lining. Multi-Cal™ provides effective antibacterial action while promoting healing and remineralization.
Key Features
- Calcium hydroxide paste with pH >12
- Bactericidal and bacteriostatic
- Radiopaque for easy radiographic tracking
- Smooth, creamy consistency for easy handling
- Supports dentin bridge formation and healing
Common Applications
- Temporary or intermediate root canal therapy
- Direct and indirect pulp capping
- Pulpotomy and pulpal curettage
- Cavity lining and base placement
Technical Specifications
Product Name: Multi-Cal™ Calcium Hydroxide Preparation Kit
Product Type: Calcium Hydroxide Paste
Consistency: Smooth, creamy
pH: >12
Radiopacity: Yes
Properties: Bactericidal, bacteriostatic
Manufacturer: Pulpdent
Customer Ratings
Rating: 4.8 out of 5 (Based on verified reviews)
Customer Feedback
Excellent consistency and antibacterial effect
A go-to product for pulp therapy and root canal support
9. Vista-Cal™ – Visco-Tips™

Product Description
Vista-Cal™ Visco-Tips™ from Vista Dental Products are precision applicator tips designed to improve the delivery of viscous materials such as calcium hydroxide. Their bendable, flexible design enables accurate placement even in hard-to-reach areas.
Product Overview
These tips feature the Secure-Lock™ hub design for added stability and safety during use. Ideal for delivering materials like Vista-Cal™ with precision and control, Visco-Tips™ enhance flowability while maintaining accuracy in confined spaces.
Key Features
- Improves flow and placement of viscous materials
- Designed for precise delivery of calcium hydroxide
- Bendable, flexible tip for optimal access
- Secure-Lock™ hub ensures a stable connection
- Enhances control in clinical applications
Common Applications
- Application of calcium hydroxide and similar materials
- Use in endodontic and restorative procedures
- Placement in narrow, curved, or posterior canals
Technical Specifications
Product Name: Vista-Cal™ – Visco-Tips™
Product Type: Applicator Tips
Compatibility: Calcium Hydroxide Delivery
Tip Type: Flexible and Bendable
Hub Design: Secure-Lock™
Manufacturer: Vista Dental Products
Customer Ratings
Rating: 4.7 out of 5 (Based on verified reviews)
Customer Feedback
Great for controlled placement — easy to maneuver
Secure connection and precise application every time
10. Glyde™ File Prep Root Canal Conditioner – Syringe Kit

Product Description
Glyde™ File Prep Root Canal Conditioner is a gel-based chelating agent and lubricant designed to assist in the mechanical and chemical preparation of root canals. Its formulation enhances cleansing, debris removal, and instrumentation accuracy.
Product Overview
Containing 10% carbamide peroxide and 15% EDTA, Glyde™ produces an effervescing action when used with sodium hypochlorite (NaOCl), helping lift dentinal shavings and debris from the canal. Its smooth, gel-like consistency adheres to files for precise placement, and the disposable tip ensures clean, single-dose applications to prevent cross-contamination.
Key Features
- 10% carbamide peroxide and 15% EDTA formulation
- Chelates and lubricates the canal for smoother instrumentation
- Effervescent action improves debris and smear layer removal
- Gel consistency clings to files for accurate delivery
- Disposable tips minimize contamination risk
- Enhances cleansing when used with NaOCl
Common Applications
- Root canal conditioning and smear layer removal
- Chelation and lubrication during instrumentation
- Used in conjunction with NaOCl for effective debridement
Technical Specifications
Product Name: Glyde™ File Prep Root Canal Conditioner – Syringe Kit
Product Type: Endodontic Chelating Agent / Lubricant
Formulation: 10% Carbamide Peroxide, 15% EDTA
Consistency: Smooth Gel
Delivery System: Syringe with Disposable Tips
Manufacturer: Dentsply Sirona
Customer Ratings
Rating: 4.9 out of 5 (Based on verified reviews)
Customer Feedback
Excellent for softening canals and debris removal
Effervescent action and single-use tips make it both safe and effective